British journal of anaesthesia
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The fresh gas utilization (FGU) of a semi-closed breathing system is defined as the ratio of the amount of gas reaching the patient's lungs to the total amount of fresh gas flowing into the breathing system. It indicates to what extent a breathing system conserves anaesthetic gases and provides inspired gas concentrations as close as possible to those in the fresh gas, even at low fresh gas flows (FGF). ⋯ None of the systems tested showed the characteristics of an ideal system which would reach 100% FGU with an FGF less than minute volume. At FGF 3 litre min-1, FGU was: Gambro Engström Elsa 97.8%, Siemens Servo Ventilator 900 D with circle system 96.1%, Dräger Cicero 93.4%, Ohmeda Modulus II Plus 93.1%, Dräger 8 ISO 92.3%, Dräger AV1 87.6%, Megamed 700A 77.0% and Siemens Ventilator 710 74.1%.
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Randomized Controlled Trial Comparative Study Clinical Trial
Double-blind comparison of the morphine sparing effect of continuous and intermittent i.m. administration of ketorolac.
The morphine sparing effect of ketorolac 10 mg administered 4-hourly by intermittent i.m. injection was compared with a continuous i.m. infusion in a double-blind, placebo-controlled trial in patients undergoing upper abdominal surgery. During the 48-h postoperative period, each patient was provided with a patient-controlled analgesia (PCA) system which delivered bolus doses of morphine and administered the intermittent i.m. doses automatically via a computer controlled pump. ⋯ In the second 24 h and over the entire 48 h of the study, patients in the continuous group required significantly less morphine than those in the placebo group. The intermittent group used less than the placebo group, but this was not significant.