British journal of anaesthesia
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Review Meta Analysis
Association between frailty and clinical outcomes in surgical patients admitted to intensive care units: a systematic review and meta-analysis.
Preoperative frailty may be a strong predictor of adverse postoperative outcomes. We investigated the association between frailty and clinical outcomes in surgical patients admitted to the ICU. ⋯ PROSPERO CRD42020210121.
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On March 4, 2018, two casualties collapsed on a park bench in Salisbury, Wiltshire, UK. They were later discovered to have been the victims of an attempted murder using the Soviet-era Novichok class of nerve agent. ⋯ Before the COVID-19 pandemic, the Salisbury and Amesbury incidents were the longest-running major incidents in the history of the UK National Health Service. This narrative review seeks to reflect on the lessons learned from these chemical incidents, with a particular focus on hospital and local organisational responses.
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Randomized Controlled Trial Multicenter Study Comparative Study
Intravenous iron to treat anaemia following critical care: a multicentre feasibility randomised trial.
Anaemia is common and associated with poor outcomes in survivors of critical illness. However, the optimal treatment strategy is unclear. ⋯ ISRCTN13721808 (www.isrctn.com).
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Artificial intelligence (AI) has the potential to personalise mechanical ventilation strategies for patients with respiratory failure. However, current methodological deficiencies could limit clinical impact. We identified common limitations and propose potential solutions to facilitate translation of AI to mechanical ventilation of patients. ⋯ Development of algorithms should involve prospective and external validation, with greater code and data availability to improve confidence in and translation of this promising approach.
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With healthcare systems rapidly becoming overwhelmed and occupied by patients during a pandemic, effective and safe care for patients is easily compromised. During the course of the current pandemic, numerous treatment guidelines have been developed and published that have improved care for patients with COVID-19. Certain lessons have only been learned during the course of the outbreak, from which we can learn for future pandemics. This editorial aims to raise awareness about the importance of timely stockpiling of sufficient amounts of personal protection equipment and medications, adequate oxygen supplies, uninterrupted electricity, and fair locally adapted triage strategies.