British journal of anaesthesia
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Br J Anaesth
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Randomized Controlled Trial
Propofol plus low dose dexmedetomidine infusion and postoperative delirium in older patients undergoing cardiac surgery.
Postoperative delirium (POD) is a frequent complication in older patients. Dexmedetomidine might be effective in decreasing the incidence of POD. We hypothesised that adding low-dose rate dexmedetomidine infusion to a propofol sedation regimen would have fewer side-effects and would counteract the possible delirium producing properties of propofol, resulting in a lower risk of POD than propofol with placebo. ⋯ NCT03388541.