British journal of anaesthesia
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Multicenter Study Observational Study
Outcomes of the NHS England national extracorporeal membrane oxygenation service for adults with respiratory failure: a multicentre observational cohort study.
Extracorporeal membrane oxygenation (ECMO) is increasingly used to support adults with severe respiratory failure refractory to conventional measures. In 2011, NHS England commissioned a national service to provide ECMO to adults with refractory acute respiratory failure. Our aims were to characterise the patients admitted to the service, report their outcomes, and highlight characteristics potentially associated with survival. ⋯ NCT03979222.
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Randomized Controlled Trial
Brainwave entrainment to minimise sedative drug doses in paediatric surgery: a randomised controlled trial.
Anaesthetic drugs may cause neuroapoptosis in children and are routinely used off-label in specific age groups. Techniques that reduce anaesthetic drug dose requirements in children may thus enhance the safety of paediatric sedation or anaesthesia. Brainwave entrainment, notably in the form of auditory binaural beats, has been shown to have sedative effects in adults. We evaluated the influence of brainwave entrainment on propofol dose requirements for sedation in children. ⋯ DRKS00005064.