International journal of clinical practice
-
Int. J. Clin. Pract. · Nov 2020
Observational StudyMonocentric single-arm study of desmopressin acetate efficacy on nocturnal polyuria in the elderly.
We designed a retrospective, monocentric, observational study to assess the efficacy and short-term side effect profile of desmopressin, a synthetic analogue of antidiuretic hormone, in 42 elderly patients affected by nocturnal polyuria (NP), a subset of nocturia (nocturnal overproduction of urine at night), which is characterised by nocturnal urine volume (NVU) exceeding 33% of the 24-hours total urine output. ⋯ Our findings show efficacy of desmopressin in the elderly for NP treatment supporting further clinical trials in larger cohorts of patients.
-
Int. J. Clin. Pract. · Nov 2020
Review Meta Analysis Clinical Trial Controlled Clinical TrialEducational interventions to improve outcomes in patients with atrial fibrillation--a systematic review.
Atrial fibrillation (AF) is an emerging epidemic associated with poor mental health and quality of life, as well as morbidity and mortality. Whilst other cardiovascular conditions have demonstrated positive outcomes from educational programmes, this approach is not well integrated in clinical practice in patients with AF. Though evidence in this area is mounting, a thorough overview seems to be lacking. ⋯ Educational interventions significantly decrease the number of serious adverse events in patients with AF and seem to have a positive impact on mental health and self-reported quality of life. However, the evidence is limited, and more studies are warranted.
-
Int. J. Clin. Pract. · Nov 2020
ReviewPersonal protective equipment (PPE) and infection among healthcare workers - what is the evidence?
The worldwide outbreak of coronavirus disease-19 (COVID-19) has already put healthcare workers (HCWs) at a high risk of infection. The question of how to give HCWs the best protection against infection is a priority. ⋯ Covering more of the body, and a higher-level specification of masks and respirators could provide better protection for HCWs. Community mask usecould be beneficial. High quality studies still need to examine the protection of PPE against COVID-19.