International journal of clinical practice
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Int. J. Clin. Pract. · Dec 2020
Clinical Evaluation of Plasma Coagulation Parameters in Patients with Advanced-stage Non-small cell Lung Cancer Treated with Palliative Chemotherapy in China.
Blood coagulation parameters are colossally important for clinical evaluation of palliative chemotherapy; however, this niche was not explored earlier for advanced-stage non-small cell lung cancer (NSCLC). Study focuses to explore the clinical relevancy of Coagulation parameters; prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen (FIB), D-dimer and international normalised ratio (INR) and their response to palliative chemotherapy in advanced-stage NSCLC. ⋯ The high range of PT, FIB and D-dimers was associated with poor prognosis of advanced-stage NSCLC. Our findings also confirmed that patients on 3-drugs regimen showed longer PFS compared with 2-drugs regimen.
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Int. J. Clin. Pract. · Dec 2020
Randomized Controlled Trial Multicenter StudyEffect of Electroacupuncture in Pre- and Postmenopausal Women with Stress Urinary Incontinence.
To evaluate the effect of electroacupuncture and assess the impact of menopausal status in women with stress urinary incontinence or stress-predominant mixed urinary incontinence. ⋯ This subgroup analysis indicated that electroacupuncture can improve the symptoms of urinary incontinence in women with stress urinary incontinence or stress-predominant mixed urinary incontinence and that menopausal status may not affect the effects of electroacupuncture in subjects.
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Int. J. Clin. Pract. · Dec 2020
Observational StudyAssessment of Individuals' Attitude, Knowledge and Anxiety Toward Covid 19 At The First Period of the Outbreak in Turkey: A Web Based Cross-Sectional Survey.
The aim of this study is to evaluate the attitude, knowledge and anxiety status of individuals about COVID-19 at the first period of the outbreak. ⋯ According to the results of the study individuals usually had better awareness and positive attitudes towards COVID-19 pandemic, but there were also things that needed improvement. The most important measure to be taken in order to prevent anxiety from increasing is to ensure the correct access of information and to establish psychological support lines.
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Int. J. Clin. Pract. · Dec 2020
Investigation of monocyte HDL ratio as an indicator of inflammation and complete blood count parameters in patients with acne vulgaris.
Acne vulgaris is a common inflammatory skin disease that affects the pilosebaceous unit. Increased sebum production, hyperkeratosis in follicular infundibulum, inflammation and Propionibacterium acnes are among aetiological factors. Complete blood count (CBC) parameters are used as diagnosis biomarkers for many diseases related with inflammatory processes. Although monocyte/HDL ratio (MHR) has been defined as an inflammatory marker recently, we did not come across any studies about MHR in acne, which is known to be an inflammatory disease. The present study was conducted to compare CBC parameters and MHR levels in acne vulgaris patients and healthy controls (HCs). ⋯ We believe that prospective studies consisting of large patient series are needed to understand whether CBC parameters and MHR ratio can be used as an inflammatory marker in acne vulgaris patients.
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Int. J. Clin. Pract. · Dec 2020
High Fitness Might be Associated with the Development of New-Onset Atrial Fibrillation in Obese Non-Athlethic Adults.
Data on the association between AF and fitness are conflicting. ⋯ Our findings suggest that high fitness might be associated with increased AF risk among obese subjects.