International journal of clinical practice
-
Int. J. Clin. Pract. · Oct 2021
Prior benzodiazepine use and mortality among adult patients with sepsis: A retrospective population-based cohort study in South Korea.
This study investigated whether long-term benzodiazepine use is associated with increased 90-day mortality among patients with sepsis. ⋯ Long-term benzodiazepine use is associated with increased 90-day mortality among adult patients with sepsis compared with non-users. This association was more evident in benzodiazepine users with other psychiatric diseases, such as depression or anxiety disorder.
-
Int. J. Clin. Pract. · Oct 2021
Observational StudyAn Emergency Plan for Management of COVID-19 Patients in Rural Areas.
To describe the experience of six hospitals in the management of COVID-19 patients in rural areas through an assessment of proportions, types and clinical outcomes of remote clinical interventions. ⋯ Our findings demonstrate significant impact of the remote pharmacist interventions on both medicines use and clinical outcomes of COVID-19 patients in rural areas. Pharmacists in developing countries should be supported to implement remote clinical services to provide patients in rural places with optimal care.
-
Int. J. Clin. Pract. · Oct 2021
Performance of the CURB-65, ISARIC-4C, and COVID-GRAM scores in terms of severity for COVID-19 patients.
In the COVID-19 pandemic, difficulties have been experienced in the provision of healthcare services because of excessive patient admissions to hospitals and emergency departments. It has become important to use clear and objective criteria for the early diagnosis of patients with high-risk classification and clinical worsening risk. ⋯ Among the scoring systems assessed, CURB-65 score had better performance in predicting in-hospital mortality and ICU requirement in COVID-19 patients. ISARIC-4C has been found successful in identifying low-risk patients and the use of the ISARIC-4C score with CURB-65 increases the accuracy of risk assessment.
-
Int. J. Clin. Pract. · Oct 2021
Causes of in-hospital death in patients with type 2 diabetes with micro- and macrovascular complications in Taiwan.
Diabetes mellitus is a major cause of death worldwide, including Taiwan. The mortality data of the subsets of patients who suffered from microvascular or macrovascular complications is limited. The aim of this study was to investigate the causes of in-hospital death of patients with type 2 diabetes, especially the patients with microvascular, macrovascular and both micro-macrovascular complications. ⋯ Pneumonia increased risk of in-hospital death among the type 2 diabetic patients with microvascular, macrovascular and both micro-macrovascular complications. Therefore, efforts aim at preventing pneumonia or decreasing its severity may increase survival.
-
Int. J. Clin. Pract. · Oct 2021
Annexin A1 as a Potential Prognostic Biomarker for COVID-19 Disease: Case-Control Study.
Annexin A1 (AnxA1) is an important endogenous glucocoticoid protein that contributes to the suppression of inflammation by limiting the production of neutrophil and pro-inflammatory cytokines. This study aims to determine the clinical predictivity value of blood AnxA1 levels in patients with mild and severe-critical pneumonia induced by COVID-19. ⋯ AnxA1 levels may be a beneficial biomarker in the diagnosis of COVID-19 pneumonia and in predicting the need for ICU treatment in patients with COVID-19 pneumonia at the time of admission to the emergency department.