International journal of clinical practice
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Int. J. Clin. Pract. · Jan 2023
Changes in Serum Concentrations of Bone Turnover Markers in Healthy Pregnant Women.
Changes in bone metabolism during pregnancy have not received sufficient attention because of the lack of effective screening tools. Bone turnover markers (BTMs) could reflect the changes of bone metabolism. Currently, reference intervals for bone metabolism during normal pregnancy are inconclusive. This study aimed to determine reference intervals for BTMs in pregnant women taking prenatal care and to facilitate clinical research on diseases affecting bone metabolism during pregnancy. ⋯ This study established reference intervals for BTMs in pregnant women and observed the changes in BTMs during the different trimesters of pregnancy. The present findings can help in clinical monitoring of the effects of pregnancy diseases on the bone metabolism of pregnant women.
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Int. J. Clin. Pract. · Jan 2023
The Relationship between the Serum NLRP1 Level and Coronary Lesions in Patients with Coronary Artery Disease.
The pathogenesis of coronary artery disease is complex, and inflammation is one of the regulatory factors. The nucleotide-binding oligomerization domain (NOD)-like receptor protein 1 (NLRP1) plays an important role in the cellular inflammatory response, cell apoptosis, cell death, and autoimmune diseases. Whether the level of NLRP1 is related to the severity of coronary artery stenosis in patients with coronary artery disease (CAD) has not been reported. ⋯ The serum NLRP1 level is increased in patients with UA, which is increased with the increasing severity of coronary lesions.
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Int. J. Clin. Pract. · Jan 2023
Review Meta AnalysisPhysical and Rehabilitation Therapy for Overactive Bladder in Women: A Systematic Review and Meta-Analysis.
To compare the effects of different physical and rehabilitation therapies on women with overactive bladder (OAB). ⋯ All physical and rehabilitation therapies can improve daytime micturition and nocturia frequency in OAB. PTNS, BT + ES, and BT + BF + ES were the priority therapies.
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Int. J. Clin. Pract. · Jan 2023
ReviewEffects of Oral Inflammatory Diseases and Oral Hygiene on Atrial Fibrillation: A Systematic Review.
Research evidence suggests a link between periodontitis (PD) and atrial fibrillation, but the nature of this link is unclear. This study aimed to systematically review and evaluate the association between PD, other oral diseases, and atrial fibrillation and the role of oral hygiene in preventing atrial fibrillation. ⋯ Regular and moderate oral hygiene, frequent tooth brushing, and prevention of PD and other oral inflammatory diseases could reduce the occurrence of atrial fibrillation. It is recommended to strengthen the popularization of oral health knowledge in the publicity related to atrial fibrillation.
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Int. J. Clin. Pract. · Jan 2023
Randomized Controlled TrialEffect of Humulus lupulus L. (Hop) on Postmenopausal Sexual Dysfunction: A Randomized Clinical Trial.
Female sexual dysfunction is a common distressing problem among women, which may result from reducing circulating endogenous estrogen. Humulus lupulus L. (hop) has antioxidant, anti-inflammatory, anticancer, and estrogenic properties. Therefore, this study aimed to assess the efficacy of hop on postmenopausal sexual dysfunction. ⋯ Vaginal hop was as effective as estradiol in improving the sexual dysfunction among postmenopausal women with no adverse events. This trial is registered with IRCT20210405050859N1.