International journal of clinical practice
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Int. J. Clin. Pract. · Mar 2021
Multicenter StudyPrevention of long-lasting atrial fibrillation through antitachycardia pacing in DDDR pacemakers.
The MINERVA trial showed that in pacemaker patients with atrial fibrillation (AF) history, DDDRP pacing combining three algorithms - (a) atrial antitachycardia pacing with Reactive ATP enabled, (b) atrial preventive pacing and (c) managed ventricular pacing (MVP)-may effectively delay progression to persistent/permanent AF compared with standard DDDR pacing. We performed a comparative non-randomised evaluation to evaluate if Reactive ATP can be the main driver of persistent/permanent AF reduction independently on preventive pacing. ⋯ In a real-world population of dual-chamber pacemaker patients with AF history, the use of Reactive ATP is associated with a low incidence of persistent AF, highlighting that the positive results of the MINERVA trial were related to the effectiveness of Reactive ATP rather than to preventive pacing.
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Int. J. Clin. Pract. · Mar 2021
Multicenter Study Observational StudyGender-related clinical and management differences in patients with chronic heart failure with reduced ejection fraction.
Gender-related differences have been described in the clinical characteristics and management of patients with chronic heart failure with reduced ejection fraction (HFrEF). However, published data are conflictive in this regard. ⋯ In summary, although management seemed to be equivalent between genders, women tended to present with more symptoms, require hospitalisation more frequently and have different comorbidities than men. These results highlight the importance of gender-related differences in HFrEF and call for further research to clarify the causes of these disparities. Gender-specific recommendations should be included in future guidelines in HFrEF.
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Int. J. Clin. Pract. · Mar 2021
Multicenter Study Observational StudyAtrial fibrillation pattern, left atrial diameter and risk of cardiovascular events and mortality. A prospective multicenter cohort study.
There are conflicting evidence on the association between atrial fibrillation (AF) pattern, such as persistent/permanent (Pers/Perm) and paroxysmal (PAF) AF and risk of ischemic events. We investigated if left atrial diameter (LAd) may affect the risk of cardiovascular outcomes according to AF pattern. ⋯ LAd is a simple parameter that can be obtained in virtually all AF patients and can provide prognostic information on the risk of CVEs, MACE and CV death regardless of AF pattern.
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Int. J. Clin. Pract. · Feb 2021
Multicenter StudyEffects of Mirabegron on JJ Stent-Related Symptoms: A Multicentric Study.
To investigate the effect of mirabegron 50 mg/daily for JJ stent-related symptoms after ureteroscopic stone surgery. ⋯ Daily use of 50 g of mirabegron significantly improved stent-related symptoms, sexual matters and quality of life.
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Int. J. Clin. Pract. · Jan 2021
Multicenter StudyInfluenza Vaccination Rates, Knowledge, Attitudes and Behaviors of Healthcare Workers in Turkey: A Multicenter Study.
Influenza vaccination is the most effective method in prevention of influenza disease and its complications. Our study aimed to investigate the rates of vaccination and the behaviours and attitudes against the vaccine in healthcare workers in Turkey. ⋯ The rates of influenza vaccination in healthcare workers in Turkey are quite low. False knowledge and attitudes on the vaccine and disease are seen as the most important reasons to decline vaccination. It is important to detect reasons for anti-vaccination and set a course in order to increase the rates of vaccination.