International journal of clinical practice
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisAssociation between Genetic Polymorphisms and Risk of Kidney Posttransplant Diabetes Mellitus: A Systematic Review and Meta-Analysis.
The purpose of this study was to clarify the role of genetic factors on posttransplant diabetes mellitus (PTDM) risk. ⋯ The gene polymorphisms of TCF7L2 rs7903146, KCNQ1 rs2237892, and KCNJ11 rs5219 may predispose kidney transplant recipients to PTDM. Large sample size studies on diverse ethnic populations were warranted to confirm our findings.
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisAssociation between Genetic Polymorphisms and Risk of Kidney Posttransplant Diabetes Mellitus: A Systematic Review and Meta-Analysis.
The purpose of this study was to clarify the role of genetic factors on posttransplant diabetes mellitus (PTDM) risk. ⋯ The gene polymorphisms of TCF7L2 rs7903146, KCNQ1 rs2237892, and KCNJ11 rs5219 may predispose kidney transplant recipients to PTDM. Large sample size studies on diverse ethnic populations were warranted to confirm our findings.
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisOpium Use and Cancer Risk: A Comprehensive Systematic Review and Meta-Analysis of Observational Studies.
Epidemiological studies have reported inconsistent associations between opium use and cancer risk. We therefore conducted a systematic review and meta-analysis to investigate the relationship between opium use and cancer risk. ⋯ Our findings showed that opium use, particularly in the form of teriak, is a risk factor for cancer.
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Int. J. Clin. Pract. · Jan 2022
Review Meta AnalysisOpium Use and Cancer Risk: A Comprehensive Systematic Review and Meta-Analysis of Observational Studies.
Epidemiological studies have reported inconsistent associations between opium use and cancer risk. We therefore conducted a systematic review and meta-analysis to investigate the relationship between opium use and cancer risk. ⋯ Our findings showed that opium use, particularly in the form of teriak, is a risk factor for cancer.
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Int. J. Clin. Pract. · Jan 2022
Review Case ReportsA Case of Type 1 Triallelic Patterns at D5S818, D18S51, D6S1043, and FGA Demonstrated by Short Tandem Repeat Analysis.
The triallelic pattern of short tandem repeat (STR) is rare; especially, the case where this pattern exists at 4 loci has not been reported. Here, we report the type 1 triallelic patterns at D5S818, D18S51, D6S1043, and FGA from a Chinese family, which were observed during our routine chimerism assays. Before hematopoietic stem cell transplantation, the blood sample of the certain patient was analyzed by performing chimerism analysis. ⋯ Altogether, we presented a pedigree, in which the triallelic pattern was linked by inheritance in the family. This is the first reported case of the triallelic pattern at D5S818, D18S51, D6S1043, and FGA all around the world. We hope that in the future there will be any tools to achieve accurate verification against this possibility.