The British journal of surgery
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Breast angiosarcoma is a rare disease mostly observed in breast cancer (BC) patients who have previously received radiotherapy (RT). Little is known about angiosarcoma aetiology, management, and outcome. The study aim was to estimate risk and to characterize breast angiosarcoma in a Swedish population-based cohort. ⋯ Breast angiosarcoma is a rare disease strongly associated with a history of previous BC RT. Overall survival is poor with high rates of local recurrences and distant metastasis.
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The process of innovation is always valuable and can lead to great advances, both intended and unanticipated. However, the outcomes must always be carefully examined in terms of metric which considers more than could ever be tested in a RCT.