The British journal of surgery
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Randomized Controlled Trial Clinical Trial
Prospective randomized double-blind trial of neurolytic coeliac plexus block in patients with pancreatic cancer.
In a randomized double-blind study the efficacy of neurolytic coeliac plexus block (NCPB) was compared with pharmacological therapy in the treatment of pain from pancreatic cancer. ⋯ NCPB was associated with a reduction in analgesic drug administration and drug-related adverse effects, representing an effective tool in the treatment of pancreatic cancer pain.
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Randomized Controlled Trial Clinical Trial
Enteral nutrition is superior to parenteral nutrition in severe acute pancreatitis: results of a randomized prospective trial.
Parenteral nutrition is well established for providing nutritional support in acute pancreatitis while avoiding pancreatic stimulation. However, it is associated with complications and high cost. Benefits of enteral feeding in other disease states prompted a comparison of early enteral feeding with total parenteral nutrition in this clinical setting. ⋯ This study suggests that early enteral nutrition should be used preferentially in patients with severe acute pancreatitis.
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Randomized Controlled Trial Clinical Trial
Randomized controlled trial of prophylactic chest physiotherapy in major abdominal surgery.
This randomized controlled study evaluated the clinical benefit and physiological effects of prophylactic chest physiotherapy in open major abdominal surgery. ⋯ Preoperative chest physiotherapy reduced the incidence of postoperative pulmonary complications and improved mobilization and oxygen saturation after major abdominal surgery.
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Randomized Controlled Trial Clinical Trial
Long-term oral administration of branched chain amino acids after curative resection of hepatocellular carcinoma: a prospective randomized trial. The San-in Group of Liver Surgery.
Live cirrhosis is a state of protein calorie malnutrition which may induce various complications. This study aimed to elucidate if long-term nutritional support with branched chain amino acids (BCAAs) is effective after hepatic resection for hepatocellular carcinoma (HCC). ⋯ Long-term oral nutritional support with BCAAs after resection of HCC is beneficial in improving clinical features and laboratory data without increasing the rate of tumour recurrence, particularly in patients with advanced cirrhosis or after major hepatic resection.
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Randomized Controlled Trial Clinical Trial
Risk factors for surgical treatment in the Dutch Gastric Cancer Trial.
A multicentre randomized study of surgical treatment of gastric cancer has shown increased mortality and morbidity rates in patients having D2 resection. The aim of this report is to analyse risk factors in these patients. ⋯ The cumulative mortality risks of these factors should be considered carefully when planning surgery for individual patients.