Journal of clinical monitoring and computing
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J Clin Monit Comput · Oct 2009
Clinical TrialA novel electronic algorithm for detecting potentially insufficient anesthesia: implications for the prevention of intraoperative awareness.
A recent clinical trial compared a minimum alveolar concentration (MAC)-based protocol to an electroencephalography (EEG)-based protocol for the prevention of intraoperative awareness. One limitation of this study design is that MAC-based protocols are not sensitive to the use of intravenous agents, while EEG-based protocols are. Our objective was to develop a MAC alert that incorporates intravenous agents. ⋯ Our novel electronic alerting system incorporates both age-adjusted MAC and intravenous anesthesia, and triggers with a higher frequency in cases of awareness. These data suggest the potential for our system to alert clinicians to insufficient anesthesia.
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J Clin Monit Comput · Oct 2009
Monitoring of reactive hyperemia using photoplethysmographic pulse amplitude and transit time.
Peripheral arterial tonometry and Ultrasound measurement of flow mediated dilation have been the widely reported noninvasive techniques to assess vasodilation during reactive hyperemia (RH). ⋯ Results suggests that PTT response reflects the myogenic components in the early part of RH and PPG amplitude response reflects the metabolic component reinforcing the later course of RH. PPG amplitude and PTT can be used to quantify the changes in diameter and tone of the vessel wall, respectively during RH. The collective responses of PPG amplitude and PTT can be more appropriate to facilitate PPG technique for monitoring of vasodilation caused by RH.