Journal of clinical monitoring and computing
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The Systolic pressure variation (SPV) is known to be a sensitive indicator of hypovolemia. However, the SPV may be elevated due to other reasons, such as changes in lung compliance or tidal volumes. Using the SPV to monitor the hemodynamic status of patients in the prone position may, therefore, be problematic due to possible effects of increased abdominal pressure on both venous return and lung compliance. The purpose of this study is to examine whether or not the SPV changes significantly when placing the patient in the prone position. ⋯ This study is important because it shows for the first time that the SPV does not change significantly in the prone position, and may therefore continue to be used as an indicator of the volume status. It also would appear to indicate that our methods for protecting the chest and abdomen in the prone position are effective.
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J Clin Monit Comput · Oct 2009
Clinical TrialA novel electronic algorithm for detecting potentially insufficient anesthesia: implications for the prevention of intraoperative awareness.
A recent clinical trial compared a minimum alveolar concentration (MAC)-based protocol to an electroencephalography (EEG)-based protocol for the prevention of intraoperative awareness. One limitation of this study design is that MAC-based protocols are not sensitive to the use of intravenous agents, while EEG-based protocols are. Our objective was to develop a MAC alert that incorporates intravenous agents. ⋯ Our novel electronic alerting system incorporates both age-adjusted MAC and intravenous anesthesia, and triggers with a higher frequency in cases of awareness. These data suggest the potential for our system to alert clinicians to insufficient anesthesia.