Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
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Comparative Study
Waterpipe tobacco smoking and cigarette smoking: a direct comparison of toxicant exposure and subjective effects.
Waterpipe tobacco smoking is increasing worldwide and is believed by many users to be less harmful and addictive than cigarette smoking. In fact, waterpipe tobacco and cigarette smoke contain many of the same chemicals, and users are exposed to the dependence-producing drug nicotine as well as other smoke toxicants. The subjective effect profile of these 2 tobacco use methods has not been compared directly, though this information is relevant to understanding the risk of dependence development. ⋯ Relative to a cigarette, waterpipe tobacco smoking was associated with similar peak nicotine exposure, 3.75-fold greater COHb, and 56-fold greater inhaled smoke volume. Waterpipe and cigarette influenced many of the same subjective effect measures. These findings are consistent with the conclusion that waterpipe tobacco smoking presents substantial risk of dependence, disease, and death, and they can be incorporated into prevention interventions that might help deter more adolescents and young adults from experimenting with an almost certainly lethal method of tobacco use.
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To examine the time patterns and predictors of initiating a quit attempt and subsequent sustained abstinence among youth smokers after receiving a telephone smoking cessation intervention. ⋯ Our findings support the "catastrophic" pathway of youth smokers initiating a quit attempt. Counselors should capture the quitting momentum and motivate youth smokers to quit immediately. Interventions should include a health assessment and discussion of smokers' physical fitness. During the first week of abstinence, intensive monitoring of withdrawal symptoms, together with booster counseling, is helpful in preventing smoking relapse and could remotivate those who fail to sustain their quit attempt.
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Sensory perception is a key determinant of smoking behavior and, therefore, reinforcement and addiction. The tobacco industry has conducted extensive research on the chemosensory and physiological effects of menthol in tobacco smoke and has actively promoted menthol's sensory characteristics. ⋯ The industry considers menthol to be an important tool for modulating the sensory effects of nicotine in different product variations, particularly those designed to be acceptable to "starters" or people interested in quitting. Regulatory efforts should consider that menthol enables the tobacco industry to customize a highly addictive product in a manner that contributes to initiation and deters cessation due to its chemosensory effects.
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Comparative Study
Behavioral effects of nicotine withdrawal differ by genetic strain in male and female adolescent rats.
Gender and ethnicity are powerful predictors of initiation and maintenance of cigarette smoking in adults but less is known about their role in smoking in adolescents. Consistent with human studies, rat models also reveal sex and strain differences in response to nicotine administration. ⋯ Results indicate that nicotine withdrawal in adolescent rats depends on sex and strain.
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Randomized Controlled Trial Multicenter Study
Brief smoking cessation intervention in relation to breast cancer surgery: a randomized controlled trial.
Smokers are more prone to develop postoperative complications. Smoking cessation intervention beginning 4-8 weeks prior to surgery improves the postoperative outcome. Cancer patients, however, often undergo surgery less than 4 weeks after diagnosis. The primary objective of this study was therefore to examine if a brief smoking cessation intervention shortly before breast cancer surgery would influence postoperative complications and smoking cessation. ⋯ Brief smoking intervention administered shortly before breast cancer surgery modestly increased self-reported perioperative smoking cessation without having any clinical impact on postoperative complications. The study adds to the body of evidence indicating that brief intervention has no clinical importance for surgical patients in regard to postoperative morbidity. Future studies should be designed to determine the optimal time of smoking cessation before surgery.