Annals of cardiac anaesthesia
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Randomized Controlled Trial
The analgesic efficacy of continuous presternal bupivacaine infusion through a single catheter after cardiac surgery.
Median sternotomy, sternal spreading, and sternal wiring are the main causes of pain during the early recovery phase following cardiac surgery. ⋯ Continuous presternal bupivacaine infusion has resulted in better postoperative analgesia, reduction in morphine requirements, shorter time to extubation, and better postoperative respiratory parameters than the control group.
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Randomized Controlled Trial
Efficacy of perioperative pregabalin in acute and chronic post-operative pain after off-pump coronary artery bypass surgery: a randomized, double-blind placebo controlled trial.
We evaluated the efficacy of perioperative pregabalin on acute and chronic post-operative pain after off-pump coronary artery bypass (OPCAB) surgery. ⋯ Perioperative pregabalin reduced pain scores at rest and deep breath and reduced consumption of tramadol in the post-operative period without delaying extubation and causing excessive sedation.
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Randomized Controlled Trial
Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery.
We studied the usefulness of regional cerebral oxygen saturation (rSO 2 ) monitoring during cardiopulmonary bypass (CPB) and evaluated effects of cerebral oxygen desaturation on the postoperative neurological outcome. ⋯ Monitoring of rSO 2 during CPB can significantly decrease the incidence of postoperative neurocognitive decline.
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Randomized Controlled Trial
Effect of levosimendan on hemodynamic changes in patients undergoing off-pump coronary artery bypass grafting: a randomized controlled study.
We tested the hypothesis that use of levosimendan would be associated with better perioperative hemodynamics and cardiac function during off-pump coronary artery bypass grafting (OPCAB) in patients with good left ventricular function. ⋯ Levosimendan significantly increased CI and decreased SVRI after OPCAB but it did not show any outcome benefit in terms of duration of ventilation and intensive care unit stay.
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Randomized Controlled Trial
The efficacy of caudal dexmedetomidine on stress response and postoperative pain in pediatric cardiac surgery.
We studied efficacy of caudal dexmedetomidine (DEX) on attenuation of perioperative stress response and postoperative pain in pediatric patients undergoing cardiac surgery. ⋯ Caudal DEX attenuated stress response to surgical trauma and provided better postoperative analgesia.