Undersea Hyperbar M
-
Undersea Hyperbar M · May 2014
ReviewAdvances in the therapy of hyperoxia-induced lung injury: findings from animal models.
Oxygen therapy is one of the most widely used clinical interventions to counteract insufficient pulmonary oxygen delivery in patients with severe lung injury. However, prolonged exposure to hyperoxia at elevated partial pressure leads to inflammation and acute lung injury. ⋯ In this paper, we briefly summarized the advances in the therapies of hyperoxia-induced lung injury on the basis of its pathogenesis. We hope our summary will help provide evidence for further investigation of therapeutic measures for hyperoxia-induced lung injury.
-
Undersea Hyperbar M · Jan 2014
Review Case ReportsFrostbite of both first digits of the foot treated with delayed hyperbaric oxygen:a case report and review of literature.
Frostbite is an uncommon event that can occur from exposure to temperatures below -4 degrees C and can lead to potential serious tissue damage and necrosis. This in turn can result in debilitating amputations in otherwise healthy people. The pathophysiological mechanisms of frostbite have marked similarities to those seen in thermal burns, ischemia/reperfusion injuries and crush injuries--i.e., non-healing wounds and inflammatory processes. These injuries are commonly treated with hyperbaric oxygen therapy. ⋯ Based on our case report as well as the literature and the mechanisms of hyperbaric oxygen, we make the recommendation that this therapy be considered as an addition to the multidisciplinary treatment of frostbite, even after significant delay of treatment.
-
Undersea Hyperbar M · Jul 2013
ReviewPotential roles of hyperbaric oxygenation in the treatments of brain tumors.
Over the past 50 years hyperbaric oxygen (HBO2) therapy has been used in a wide variety of medical conditions, and one of them is cancer. Many clinical studies have been conducted to evaluate potential therapeutic effects of HBO2 as a part of cancer treatment. This review briefly summaries the potential role of HBO2 therapy in the treatment of malignant tumors and radiation injury of the brain. ⋯ The possibilities of combining HBO2 therapy with radiotherapy and/or chemotherapy to overcome newly diagnosed and recurrent malignant gliomas deserve extensive clinical trials. HBO2 therapy also shows promising potential for the treatment and/or prevention of radiation injury of the brain after stereotactic radiosurgery for brain lesions. The possibilities with HBO2 to enhance the therapeutic effect of irradiation per se, and to even increase the radiation dose if there are ways to combat the side effects, should boost new scientific interest into the whole field of oncology looking for new armamentaria to fight cancer.
-
Undersea Hyperbar M · Jul 2012
ReviewThe effect of hyperbaric oxygen in crush injuries and skeletal muscle-compartment syndromes.
Crush injuries represent a spectrum of injury to body parts as result of trauma. Presentations vary from minor contusions to limb-threatening damage. Typically, the injury involves multiple tissues, from skin and subcutaneous, to muscle and tendons, to bone and joints. ⋯ The SMCS, especially in its incipient stages before a fasciotomy is required, is a therapeutic challenge since no means to arrest its progression exist other than hyperbaric oxygen (HBO2). Unfortunately, HBO2 is woefully neglected as an adjunct for managing crush injury and SMCS. Strong arguments exist for its use based on evidenced-based information and how HBO2 mitigates the pathology of these conditions.