J Trauma
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Because of the relatively large surface area of metaphyseal cancellous bone, the majority of distal femur fractures heal reliably. Nonunions of the distal femur do rarely occur, however, and the associated bone loss and soft tissue scarring can make successful treatment difficult. Few reports in the literature exist regarding the clinical and functional outcome after treatment of distal femoral nonunions. The purpose of this study was to evaluate the outcome of patients who underwent treatment of a distal femoral nonunion using a standardized treatment plan that included open reduction, internal fixation, supplemental bone graft, lag screw placement, and arthrolysis. ⋯ Distal femoral nonunions may be treated successfully with correction of deformity, stable fixed-angle internal fixation, lag screw placement, and supplemental bone grafting. Knee joint manipulation and arthrolysis are important components of the treatment plan if knee motion is limited because of fibrosis. This yields predictable functional outcome after the surgical intervention.
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Patients who undergo emergency craniotomy for head injury require vigilant postoperative (postop) care to obtain the best possible outcome. Although repeat head computed tomography (CT) scans are a key component of the management of these patients, there is no consensus on the optimal timing of the initial postop CT. ⋯ Early, if not immediate, postop CT after emergency craniotomy for head trauma appears to be warranted. We found a significant incidence of unexpected findings on postop CT and encountered avoidable delays in treatment of new or recurrent findings.
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The current shortage in intensive care unit (ICU) physician staffing coupled with Leapfrog initiatives has lead to novel ICU staffing paradigms including the use of nonsurgeon intensivists in surgical ICUs, increased development of telemedicine, and ICU regionalization.
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Sepsis stimulates the sympathetic nervous system. The resultant elevation in plasma catecholamines, both norepinephrine and epinephrine (Epi), might be expected to alter the expression of inflammatory cytokines, which may directly or indirectly influence muscle protein balance. The purpose of this study was twofold: (1) determine whether Epi per se increases cytokine expression in skeletal muscle, and (2) determine whether beta-adrenergic blockade alters the sepsis-induced expression of inflammatory cytokines and mediators of protein balance in skeletal muscle. ⋯ These results demonstrate that although Epi is capable of increasing tissue cytokines in naive rats, inhibition of the beta-adrenergic effects of catecholamines exacerbates the sepsis-induced increase of selected inflammatory cytokines. This exaggerated tissue response is associated with alterations in muscle IGF-I protein and translation initiation, which would be expected to impair tissue protein synthesis.
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Orthopedic injuries occurring in Operations Iraqi Freedom and Enduring Freedom (OIF/OEF) are complicated by infections with multidrug resistant bacteria. We describe demographics and microbiology of OIF/OEF casualties with primary and recurrent osteomyelitis. ⋯ The microbiology of osteomyelitis in veterans of OIF/OEF differs substantially depending upon whether the infection is new or recurrent. Gram-negative pathogens predominate early, being replaced with staphylococci after treatment, despite nearly universal use of gram- positive therapy.