J Trauma
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"Failure to rescue" patients with complications is a factor contributing to high mortality rates after elective surgery. In trauma, where early deaths are the primary contributors to a trauma center's mortality rate, the rescue of patients with complications might not be related to overall trauma center mortality. We assessed the extent to which trauma center mortality was reflected by the center's ability to rescue patients with major complications. ⋯ Unlike reports from elective surgery, complication rates after severe injury differ across centers and parallel mortality rates. Centers with low overall mortality are more successful at rescuing patients who experience complications. A lower risk of complications and better care of those with complications are both at play in high-performing trauma centers.
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Past studies suggest that airway pressure release ventilation (APRV) is associated with reduced sedative requirements and increased recruitment of atelectatic lung, two factors that might reduce the risk for ventilator-associated pneumonia (VAP). We investigated whether APRV might be associated with a decreased risk for VAP in patients with pulmonary contusion. ⋯ Use of APRV in patients with pulmonary contusion is associated with a reduced risk for VAP.
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The challenge of modern hand reconstruction goes beyond simple coverage. Thanks to the advances of microsurgery, there are ever-improving standards of functional and esthetic outcomes in hand reconstruction. The versatile donor site of the medial sural artery perforator flap can fulfill this purpose. ⋯ The free medial sural artery perforator flap transfer is appropriate for small- to medium-sized hand defect reconstruction. The donor site not only supplies a thin fasciocutaneous flap but also provides the option to harvest a segment of tendon or nerve graft through the same incision for composite tissue reconstruction in a single stage.
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We have previously demonstrated that valproic acid (VPA), a histone deacetylase inhibitor, and spray-dried plasma (SDP) improve early survival after lethal hemorrhage and polytrauma, but their effect on long-term survival and organ function remains untested. ⋯ In a clinically relevant lethal polytrauma model, administration of SDP significantly improves survival without any long-term organ dysfunction or complications.