J Trauma
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Comparative Study
Use of recombinant hemoglobin solution in reversing lethal hemorrhagic hypovolemic oxygen debt shock.
To compare recombinant hemoglobin solution (rHb1.1) with colloid/blood (CB) resuscitation in a hemorrhagic shock (HS) model based on oxygen debt (O2D). ⋯ Lactate and BEA accurately quantify O2D in HS and resuscitation. rHb1.1 replacement is as good as CB with regard to survival, but leads to a more uniform reperfusion and produces a more complete resolution of ischemic acidosis.
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A review is made of 16 cases of ipsilateral fractures of the scapula and clavicle treated conservatively. After a mean follow-up of 7.5 years, the functional results were good or excellent in 92% of the cases.
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To test the hypothesis that protective-preservative moderate hypothermia during uncontrolled hemorrhagic shock (UHS) in rats increases survival. ⋯ Moderate hypothermia or limited (hypotensive) fluid resuscitation --best both combined--increases survival during and after UHS in rats.
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This study used a Wiggers shock model to investigate the effect of the removal of the intestines on the outcome of hemorrhagic shock. ⋯ These experimental findings show that, in the absence of the intestines, hemorrhagic shock is associated with both an improved outcome and higher hepatic ATP levels in rats, suggesting the importance of intestinal participation in the process leading to hepatic ATP depletion as well as irreversibility in shock.