J Trauma
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Comparative Study
Different pattern of local and systemic release of proinflammatory and anti-inflammatory mediators in severely injured patients with chest trauma.
Excessive release of proinflammatory cytokines has been involved in pathogenesis of acute respiratory distress syndrome. ⋯ Highly increased concentrations of proinflammatory cytokines in BALF, but not in circulation, indicate a strong local inflammatory response early after multiple injuries combined with chest injury rather than severe systemic inflammation. In contrast, anti-inflammatory mechanisms seem to be activated locally and systemically.
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Randomized Controlled Trial Clinical Trial
Transplantation of cryopreserved cultured epidermal allografts.
To optimize cryopreservation methods for cultured epidermal allografts (CEAs) for transplantation onto wounds. ⋯ CEAs can be successfully cryopreserved for long-term storage. Upon retrieval from storage, CEAs may be used to treat partial thickness wounds.
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This study was designed to investigate the epidemiology and prognostic factors determining survival in penetrating injuries of the aorta. ⋯ Penetrating aortic injuries still have a very high mortality rate with no improvement in survival despite improved trauma services. Injury to the thoracic aorta, gunshot wounds, unrecordable blood pressure on admission, and the need for emergency room thoracotomy, are important predictors of high mortality.