Ulus Travma Acil Cer
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Ulus Travma Acil Cer · Sep 2016
Protective effect of betaine against burn-induced pulmonary injury in rats.
This study was designed to determine possible protective effect of betaine treatment against oxidative injury in pulmonary tissue induced with thermal trauma. ⋯ Treatment of rats with betaine significantly restored GSH level and Na+/K+-ATPase activity, and decreased MDA level and MPO activity. According to the findings of the present study, betaine significantly diminishes burn-induced damage in tissue.
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Ulus Travma Acil Cer · Sep 2016
Pulmonary microvascular dysfunction and pathological changes induced by blast injury in a rabbit model.
Vascular leakage has been proven to play a critical role in the incidence and development of explosive pulmonary barotrauma. Quantitatively investigated in the present study was the severity of vascular leakage in a gradient blast injury series, as well as ultrastructural evidence relating to pulmonary vascular leakage. ⋯ Primary blast wave can result in pulmonary capillary blood leakage. Blast wave can cause swelling of pulmonary capillary endothelial cells and widened gap between endothelial cells, which may be responsible for pulmonary vascular leakage.
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Ulus Travma Acil Cer · Sep 2016
Efficiacy of resveratrol and quercetin after experimental spinal cord injury.
The aim of this study was to investigate the effect of natural antioxidants resveratrol and quercetin on oxidative stress and secondary cell damage in rats with acute spinal cord injury. ⋯ Biochemical and histological staining results of present study showed that resveratrol and quercetin may be effective in preventing secondary damage in spinal cord injury.