Hepato Gastroenterol
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Hepato Gastroenterol · Sep 2012
Tumor-specific fluorescence antibody imaging enables accurate staging laparoscopy in an orthotopic model of pancreatic cancer.
Laparoscopy is important in staging pancreatic cancer, but false negatives remain problematic. Making tumors fluorescent has the potential to improve the accuracy of staging laparoscopy. ⋯ The use of fluorescence laparoscopy with tumors labeled with fluorophore-conjugated anti-CEA antibody permits rapid detection and accurate localization of primary and metastatic pancreatic cancer in an orthotopic model. The results of the present report demonstrate the future clinical potential of fluorescence laparoscopy.
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Hepato Gastroenterol · Jul 2012
Meta Analysis Comparative StudySingle-incision laparoscopic surgery vs. multiport laparoscopic surgery for colectomy: a meta-analysis of eleven recent studies.
Single-incision laparoscopic colectomy (SILC) is rapidly becoming the focal point of attraction for early adopters of minimally invasive surgery worldwide. The aim of this study was to compare SILC with multiport laparoscopic colectomy (MLC) when implemented by experienced laparoscopic surgeons. ⋯ SILC is a technically realistic and reliable approach with short-term results similar to those obtained with the MLC procedure. More large, prospective, randomized, controlled trials should be conducted to further compare the safety and efficacy of this approach.
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Hepato Gastroenterol · Jul 2012
Preoperative radiotherapy combined with S-1 for advanced lower rectal cancer: phase I trial.
S-1 based chemoradiation is the recommended treatment for rectal cancer; however, the optimal scheduling and dosing are not yet established. A Phase I study was conducted to determine the maximum tolerated dose (MTD) of S-1 with radiotherapy (RT). Endpoints were the toxicity profile of this regimen and to determine the recommended dose (RD). ⋯ The RD of S-1 with concurrent RT was determined to be 80mg/m2/day. Preoperative RT combined with S-1 was feasible and well tolerated.
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Hepato Gastroenterol · Jun 2012
Comparative StudyAdjuvant transarterial chemoembolization after curative resection of hepatocellular carcinoma: a non-randomized comparative study.
Prevention of recurrence is the most important strategy to improve long-term survival after resection of hepatocellular carcinoma (HCC). This comparative study aimed to evaluate the outcome of adjuvant transarterial chemoembolization (TACE) after hepatectomy. ⋯ Adjuvant TACE improved surgical outcome in those patients with risk factors of HCC recurrence.
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Hepato Gastroenterol · Jun 2012
Intensive pulmonary support using extracorporeal membrane oxygenation in adult patients undergoing liver transplantation.
Adult liver transplantation (LT) recipients occasionally show serious acute cardiopulmonary dysfunction, requiring intensive care. We have assessed the feasibility of extracorporeal membrane oxygenation (ECMO) support in adult LT recipients facing acute pulmonary failure and refractory to conventional mechanical ventilation and concurrent nitric oxide gas inhalation. ⋯ ECMO as rescue therapy seems beneficial to be considered as a final therapeutic option for LT recipients with refractory pulmonary dysfunction who would otherwise die due to hypoxemia.