Hepato Gastroenterol
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Hepato Gastroenterol · Mar 2005
Randomized Controlled Trial Clinical TrialIs preoperative methylprednisolone beneficial for patients undergoing esophagectomy?
This study examined whether or not preoperative administration of methylprednisolone reduces perioperative systemic inflammatory response and thus can offer clinical benefit to patients. ⋯ Preoperative methylprednisolone significantly reduces inflammatory cytokine response immediately after surgery for esophageal cancer, but its clinical benefit remains unclear.
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Hepato Gastroenterol · Nov 2004
Randomized Controlled Trial Comparative Study Clinical TrialThe value of omentoplasty in protecting colorectal anastomosis from leakage. A prospective randomized study in 126 patients.
Anastomotic leakage is a major cause of mortality in colorectal surgery. Several methods have been evaluated in order to prevent anastomotic leakage. To decrease the rate and severity of anastomotic leakage, omentoplasty (OP) has been proposed by several authors on the basis of experimental and clinical studies. A prospective, randomized trial was designed to study the influence of omentoplasty on anastomotic leakage after colorectal resection. ⋯ Omental wrap, with its mechanical and biological properties, seems to be effective in lowering the rate and the severity of anastomotic leakage after colorectal surgery.
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Hepato Gastroenterol · May 2004
Randomized Controlled Trial Comparative Study Clinical TrialStress ulcer prophylaxis in critically ill patients: a randomized controlled trial.
Critically ill patients especially who require mechanical ventilation or have coagulopathy are at increased risk for stress-related gastrointestinal hemorrhage. There are conflicting data on the efficacy and complication rates of various prophylactic regimens. ⋯ We could not show that omeprazole, famotidine, or sucralfate prophylaxis can affect already very low incidence of clinically important stress-related bleeding in high-risk surgical intensive care unit patients. Furthermore, our data suggested that especially gastric pH increasing medication could increase the risk for nosocomial pneumonia. Routine prophylaxis for stress-related bleeding even in high-risk patients seems not to be justified.
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Hepato Gastroenterol · Dec 2003
Randomized Controlled Trial Clinical TrialRemifentanil/midazolam versus tramadol/midazolam use for colonoscopy.
One of the most commonly performed outpatient procedure is colonoscopy. The pain and anxiety is frequently associated with colonoscopy. The aim of this study was to compare the effectiveness of remifentanil/midazolam, and tramadol/midazolam for iv sedation and analgesia during colonoscopy. ⋯ The patients in group T had higher pain scores. Gastroenterologist satisfaction and patient satisfaction were similar in both groups. Our results suggests that, sedoanalgesia with midazolam/remifentanil may be an alternative to sedoanalgesia with midazolam/tramadol for colonoscopy.
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Hepato Gastroenterol · Nov 2003
Randomized Controlled Trial Comparative Study Clinical TrialCoronary artery disease and upper abdominal surgery: impact of anesthesia on perioperative myocardial ischemia.
Some papers claim that epidural anesthesia and analgesia lowers the incidence of perioperative ischemic events and may have a favorable effect on perioperative cardiac morbidity and mortality. We studied the effect of epidural anesthesia and analgesia on perioperative myocardial ischemia, in a group of patients with known coronary artery disease, who underwent upper abdominal surgery. ⋯ Epidural anesthesia and analgesia reduces intraoperative and early postoperative ischemia in patients with known coronary artery disease undergoing upper abdominal surgery.