Minerva anestesiologica
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Minerva anestesiologica · Jan 2011
Randomized Controlled Trial Comparative StudyMacintosh and Glidescope® performance by Advanced Cardiac Life Support providers: a manikin study.
The aim of the present study was to assess whether the use of the Glidescope® would improve the success rates and the duration of intubation attempts during airway management when compared to direct laryngoscopy in Advanced Cardiac Life Support (ACLS) providers with no prior experience in videolaryngoscopy. ⋯ This study demonstrated that the Glidescope® videolaryngoscopy performed at least as well as conventional laryngoscopy in ACLS providers. Although simpler ventilation techniques should be applied first during critical airway management, this study suggests that, when intubation is needed, videolaryngoscopy cna be helpful.
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Subarachnoid hemorrhage (SAH) remains a serious condition with high mortality and disability. In the past decades, there have been improvements in the techniques to secure aneurysms both surgical and endovascular techniques aimed at reducing the risk of future bleeding events. ⋯ Intracranial and extracranial complications following SAH are common and impact long-term outcomes. Intensive care management of patients with SAH offers the opportunity to reduce morbidity by reducing secondary insults and preventing complications.
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Minerva anestesiologica · Jan 2011
ReviewIntraneural injections and regional anesthesia: the known and the unknown.
Peripheral nerve injury is a rare complication of regional anesthesia. Intraneural injections were once considered harbingers of neural injury with practitioners focusing on their avoidance. ⋯ We also now have a better understanding of the multifactorial nature of neurologic injury based on the nerve anatomy, site of needle insertion, bevel type, location of the needle tip, pressure achieved during injection, and underlying patient factors. Using ultrasound guidance during nerve blocks has revealed that not all intraneural injections result in injury, and its use will continue to provide insight into the mechanism of anesthetic-related nerve injury.
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Minerva anestesiologica · Jan 2011
Study of the OPRM1 A118G genetic polymorphism associated with postoperative nausea and vomiting induced by fentanyl intravenous analgesia.
Genetic polymorphisms of the μ-opioid receptor gene OPRM1 A118G have been shown to influence opioid efficacy. The association of the OPRM1 A118G genetic polymorphism with side effects, such as nausea and vomiting, caused by opioids during analgesia has not been well-represented by the literature . This study aimed to investigate whether the genetic polymorphism of OPRM1 A118G contributed to the variability in nausea and vomiting during fentanyl analgesia in patients undergoing total abdominal hysterectomy or myomectomy. ⋯ OPRM1 A118G has no effect on the individual variation of postoperative nausea and vomiting, the side effects of fentanyl analgesia, in Chinese women undergoing gynecologic surgery.
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Minerva anestesiologica · Jan 2011
The relationship between hospital volume and mortality following mechanical ventilation in the Intensive Care Unit.
A number of recent studies in North America and Europe have investigated the relationship between hospital volume and outcomes following mechanical ventilation in an Intensive Care Unit (ICU). All of these studies have revealed an association between worse outcomes and smaller-volume hospitals. This relationship has not been investigated recently in the UK. ⋯ There is no relationship between hospital volume and mortality following mechanical ventilation in the ICU. Further larger prospective studies are needed to confirm this apparent lack of a relationship between hospital volume and mortality following mechanical ventilation in ICUs in a network of hospitals in the UK.