Minerva anestesiologica
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Minerva anestesiologica · Oct 2013
Editorial CommentDo we need alternatives for bicarbonate and anion gap?
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Minerva anestesiologica · Oct 2013
Review Meta AnalysisCan the incidence of accidental dural puncture in laboring women be reduced? A systematic review and meta-analysis.
Accidental dural puncture (ADP) after epidural analgesia (EDA) for labor pain may cause severe postdural puncture headache (PDPH) and may prolong hospital stay. We aimed to identify techniques that reduce the incidence of ADP. ⋯ A reduction of the risk of ADP was found for liquid use for the loss of resistance, but only in lower quality studies. Based on current evidence, we cannot make a recommendation regarding any of the techniques under study. Therefore, clinicians should focus on measures to prevent or treat PDPH once ADP has occurred.
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Minerva anestesiologica · Oct 2013
Multicenter StudyAcute Respiratory Failure In Neutropenic Patients Is Associated With A High Post-Icu Mortality.
Few studies have evaluated outcomes of neutropenic patients admitted to the ICU at the onset of acute respiratory failure (ARF). The main objective of this study was to describe outcomes and to identify early predictors of hospital mortality in critically ill cancer patients with ARF during chemotherapy-induced neutropenia. ⋯ Our study demonstrates a meaningful ICU survival in the studied population and identified factors associated with ICU and hospital mortality. Further work is needed to address the reasons for the high post-ICU mortality rate after ARF.
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Minerva anestesiologica · Oct 2013
Modulation of inflammation during acute normovolaemic anaemia with different fluid replacement.
Acute normovolaemic anemia (ANA) frequently occurs during cardiopulmonary bypass (CPB) and major surgeries. We investigated whether fluids (with different compositions) used to replace blood elicit any degree of systemic or lung inflammatory response. ⋯ In this animal model of acute normovolemic hemodilution, fluid solutions of hydroxyethyl starch, normal saline, and modified fluid gelatine were shown to be effective in replacing blood during ANA. However, compared to HES, GEL and NS elicited a more intense systemic and lung inflammatory response.
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Minerva anestesiologica · Oct 2013
Letter Case ReportsFusarium spp: an evolving challenges to critically ill patients.