Minerva anestesiologica
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Minerva anestesiologica · Sep 2014
USE OF THE PARENTERAL ANTIBIOTIC ERTAPENEM AS SHORT TERM PROPHYLAXIS IN BARIATRIC SURGERY: A PHARMACOKINETICPHARMACODYNAMIC STUDY IN CLASS III OBESE FEMALE PATIENTS.
The objective of this study was to determine the pharmacokinetics-pharmacodynamics (PK/PD) of Ertapenem in extremely obese female patients (Body Mass Index [BMI] ≥ 40 kg/m²) undergoing bariatric surgery. ⋯ Our data suggest that in extremely obese female patients, the standard dose of 1 g i.v. Ertapenem as short term prophylaxis may not provide optimal clinical levels of free drug for prevention of surgical site infections.