Minerva anestesiologica
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Minerva anestesiologica · Nov 2016
Randomized Controlled TrialPropofol-remifentanil anesthesia for upper airway endoscopy in spontaneous breathing patients: the ENDOTANIL randomized trial.
The ENDOTANIL Trial aimed at comparing an association of target-controlled infusion (TCI) of remifentanil and propofol to TCI of propofol alone on the clinical conditions during pan endoscopy for assessment of the upper airway (pan endoscopy) performed under tubeless general anesthesia. ⋯ The adjunction of remifentanil to propofol TCI, at a dose that maintain spontaneous breathing, did not improve the conditions for pan endoscopy, but attenuates the hemodynamic response induced by upper airway stimulation.
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Minerva anestesiologica · Nov 2016
Perioperative haemodynamic goal-directed therapy and mortality: systematic review and meta-analysis with meta regression.
Recent data found that perioperative goal directed therapy (GDT) was effective only in higher control mortality rates (>20%) with a relatively high heterogeneity that limited the strength of evidence. The aim of the present meta-analysis was to clearly understand which high risk patients may benefit of GDT. ⋯ The present meta-analysis, adopting the meta-regression technique, suggests that GDT significantly reduces mortality even when the event control rate is >10%.
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Minerva anestesiologica · Nov 2016
Serum S100β as a prognostic marker in patients with non-traumatic intracranial hemorrhage.
The serum concentration of S100β protein reportedly predicts outcomes after brain injury. We examined the prognostic accuracy of S100β in patients with non-traumatic intracranial hemorrhage. ⋯ Serum S100β concentration corresponds with the severity of neurological insult and predicts poor outcome in patients with non-traumatic intracranial hemorrhage.