Minerva anestesiologica
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Minerva anestesiologica · Jan 2021
Meta AnalysisRole of dexmedetomidine in the treatment of delirium in critically ill patients: a systematic review and meta-analysis.
Although dexmedetomidine has been found to prevent delirium in critically ill patients, it is uncertain whether it can treat acute delirium. This study aimed to evaluate the efficacy and safety of dexmedetomidine in treating delirium, by analyzing and reviewing data from previous studies. ⋯ Dexmedetomidine promotes the resolution of delirium but also increases the incidence of bradycardia during treatment. Furthermore, it may be superior to haloperidol in treating delirium, although more studies are needed to confirm this.
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Minerva anestesiologica · Oct 2020
Multicenter Study Meta AnalysisEffect of volatile anesthetics on mortality and clinical outcomes in patients undergoing coronary artery bypass grafting: a meta-analysis of randomized clinical trials.
For patients undergoing coronary artery bypass grafting there is no mortality difference between volatile anaesthesia and TIVA.
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Minerva anestesiologica · Sep 2020
Meta AnalysisEffects of deep neuromuscular block on surgical workspace conditions in laparoscopic bariatric surgery: a systematic review and meta-analysis of randomized controlled trials.
Deep neuromuscular blockade For laparoscopic bariatric surgery improves surgical conditions but does not shorten surgical duration.
pearl -
Minerva anestesiologica · Sep 2020
Meta AnalysisEffects of anesthesia depth on postoperative cognitive function and inflammation: a systematic review and meta-analysis.
Postoperative cognitive dysfunction (POCD) and postoperative delirium (POD) are common postoperative complications in elderly patients. The effect of anesthesia depth on cognitive function remains unknown. We aimed to assess the correlations between anesthesia depth, cognitive function, and inflammation. ⋯ Light anesthesia was associated with a decrease in POD and may promote better neurocognitive function postoperatively in comparison with deep anesthesia.
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Minerva anestesiologica · Aug 2020
Meta AnalysisS100β as a potential biomarker of incident delirium: a systematic review and meta-analysis.
Delirium is an acute and fluctuating change in cognition, attention and consciousness, defined as an acute neuropsychiatric syndrome, but mechanism is extremely complex and still not well understood. Recently, the S100 calcium-binding protein B protein (S100β) has received attention in the biomarker research area of delirium. This meta-analysis was designed to investigate the relationship between S100β levels and delirium. ⋯ This meta-analysis provides evidence that serum S100β seems to be of limited value as a biomarker of delirium, but CSF S100β elevation may be more meaningful.