Minerva anestesiologica
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Minerva anestesiologica · Jul 2004
Multicenter Study Clinical TrialObservational study on the use of remifentanil in general anesthesia. Drug utilisation research.
The use of remifentanil in routine clinical practice during the induction and maintenance of general anesthesia as well as the quality of awakening after anesthesia and post-operative pain management have been assessed. ⋯ This Drug Utilisation Research study demonstrated that the use of remifentanil according to its peculiar pharmacological profile, such as potent opioid with rapid onset and offset of action, the synergistic effect with propofol and the right management of post-operative pain are widely consolidated in Italian clinical practice.
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Minerva anestesiologica · Jun 2004
Multicenter Study Comparative StudyA multicenter survey on anaesthesia practice in Italy.
To achieve more information on anaesthesia practice in Italy. ⋯ Some organizational problems still remain to be implemented, including the development of proper preoperative evaluation clinics and postanaesthesia care units, especially in bigger hospitals with more than 1 000 beds.
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Minerva anestesiologica · Jun 2003
Multicenter StudyA prospective, observational evaluation of a new supraglottic airway: the PAXpress.
Little information is available on efficacy and safety of the new supraglottic device, PA(Xpress), in anesthetized patients. The aim of this prospective observational study was to evaluate the use of this new supraglottic device in clinical practice. ⋯ Although further comparative, randomized studies should be advocated to better evaluate the use of this new supraglottic device, this prospective, observational study demonstrated that PA(Xpress) provides safe and effective airway control during mechanical ventilation in up to 98% of cases.
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Minerva anestesiologica · Apr 2001
Multicenter StudyEvolution in the utilization of the mechanical ventilation in the critical care unit.
Use of mechanical ventilation has increased in recent years and constitutes a major therapeutic modality in the intensive care unit (ICU). In the recent years, changes in the ventilatory modes, in the ventilatory strategies and in the weaning from mechanical ventilation have occurred. We have compared the data obtained from the Spanish ICUs in studies that were carried out in three periods of the nineties, with the aim to test whether the aforementioned innovations have modified the clinical practice. ⋯ Concerning to weaning, over the course of the decade occurred an increase in use of pressure support ventilation and spontaneous breathing trial, being this method the most frequently used at the end of the decade. The performance of the tracheostomy has been lesser and earlier over the time. The results obtained suggest that findings from research on mechanical ventilation are incorporated into clinical practice at a very slow pace whereas the evidence obtained from the clinical trials about weaning has had a better reception.
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Minerva anestesiologica · Mar 2001
Multicenter StudyUse of sedative and analgesic drugs in the first week of ICU stay. A pharmaco-epidemiological perspective.
To assess the current practice of pharmacological sedation and analgesia in patients admitted in Italian intensive care units. ⋯ Our results depict a relatively low prevalence of sedation in Italy, with the use of large number of different agents. We also observed a larger than expected use of some drugs, like propofol and fentanyl, that could be due to the unavailability of new sedative and analgesic drugs in Italy on 1994. In conclusion, Italian intensivists seem to be very conservative about the practice of pharmacological sedation in critically ill patients.