Minerva anestesiologica
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Minerva Anestesiol
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Minerva anestesiologica · Aug 2021
Observational StudyImmunosuppressive strategies in invasively ventilated ARDS COVID-19 patients.
COVID-19 is associated with elevated levels of inflammatory cytokines. We present the characteristics and outcomes of patients treated in the Intensive Care Unit (ICU) with immunosuppressive drugs, either tocilizumab or anakinra compared with controls. ⋯ In invasively ventilated COVID-19 patients, treatment with anakinra was associated with a higher probability of clinical improvement compared to tocilizumab; however, treatment with either drug did not result in clinically meaningful improvements compared with controls.