Minerva anestesiologica
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Minerva anestesiologica · May 2015
Editorial CommentRefractory Septic Shock: who and how should we purify?
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Minerva anestesiologica · May 2015
Early outcome of liver transplantation performed with organs procured from brain death donors with transient or sustained cardio-circulatory collapse.
Aim of this study was to compare early graft function after transplantation of recipients transplanted with livers procured from donors after brain death who experienced transient or sustained cardio-circulatory collapse. ⋯ The use of livers procured from donors after brain death that experienced transient or sustained cardio-circulatory collapse was associated with early graft function comparable to that of standard donors.
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Minerva anestesiologica · May 2015
Review Meta AnalysisPharmacological treatments for acute respiratory distress syndrome: systematic review.
Our objective was to systematically review the effect of pharmacological therapies on mortality in patients with acute respiratory distress syndrome (ARDS), focusing on randomized controlled trials (RCTs) published since a previous review in 2004. ⋯ Effective pharmacotherapy for ARDS remains extremely limited. Cis-atracurium is a promising treatment for early moderate-severe ARDS (using Berlin definition nomenclature) and merits further investigation in a large RCT.
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Minerva anestesiologica · May 2015
Review Meta AnalysisThe effect of analgesic modality on outcome following open liver surgery: a systematic review of post-operative analgesia.
Postoperative analgesia following liver resection remains controversial. The traditional standard of care of thoracic epidural is increasingly questioned due to perceived associated complications and delays to recovery. Evidence supporting alternative analgesic techniques is emerging however best practice is not yet established. ⋯ Epidural offered equivalent or superior pain scores when compared to alternative techniques. In summary current evidence suggests alternative analgesic modalities may provide favorable recovery outcomes following liver surgery but consistent evidence is limited. Epidurals provide superior pain relief to alternatives but this does not translate into reduced length of stay or complication rate following liver surgery.
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Minerva anestesiologica · May 2015
Randomized Controlled TrialNon Invasive Ventilation: Evaluation of CO2 washout by intentional leaking in three recent oronasal masks. A pilot study.
Many types of interfaces with intentional leaks exist for Non Invasive Ventilation. The purpose of intentional leaks is to remove CO2 from the interface, however the calibration does not allow a sufficiently large flow and rebreathing of CO2 can occur. The aim of this study was to compare the CO2 rinsing capacities of three new generation oronasal masks with intentional leaks (A: Quattro®, [Resmed]; B: Amara® [Respironics]; C: Forma® [Fisher&Paykel]) in healthy subjects. ⋯ There was no effect of mask on PtcCO2 in healthy subjects. The mask with the highest comfort rating had not the lowest rate of unintentional leaks.