Minerva anestesiologica
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Minerva anestesiologica · Jan 2012
Influence of opioid choice on mechanical ventilation duration and ICU length of stay.
The aim of this study was to assess the impact on mechanical ventilation and ICU outcomes of substituting remifentanil for sufentanil, in an analgesia-based sedation protocol. A database of data prospectively collected was retrospectively analyzed. The study was carried out in a 16-bed tertiary-care ICU. ⋯ Our study suggests that using a short-acting opiate with short context-sensitive half-life in an analgesia-based sedation protocol may significantly decrease the duration of mechanical ventilation and the ICU length of stay even though not significantly in long term sedation, while improving the achievement of sedation goals despite a lower requirement for adjunctive hypnotic agents, with no additional costs.
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Minerva anestesiologica · Jan 2012
Editorial CommentOff-pump coronary surgery: is it just a surgical matter?