Minerva anestesiologica
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Minerva anestesiologica · Apr 2024
Short-term effects of small volume saline infusion on acid base equilibrium in critically ill patients.
Short-term acid-base effects of 0.9% saline solution infusion are not well described. Aim of this study was to assess the effects of a fluid challenge with 0.9% saline in critically ill patients according to the Stewart's approach, which allows a precise determination of acid base equilibrium. ⋯ The infusion of 0.9% saline reduced strong ion difference by increasing plasma chloride concentration, with no effect on pH due to concomitant albumin dilution. Saline non-responders, characterized by the ability to excrete the sodium excess, were more likely to suffer the acidifying effects of saline infusion, while renal function did not affect the acid-base response to saline infusion.
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Minerva anestesiologica · Apr 2024
Editorial Comment LetterLong-term postoperative quality of life and choice of anesthetic agents.