Minerva anestesiologica
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Minerva anestesiologica · Mar 1996
Review[Experience of an intermediate respiratory intensive therapy in the treatment of prolonged weaning from mechanical ventilation].
109 patients who suffered from an episode of acute respiratory failure, necessitated mechanical ventilation (MV) in a general Intensive Care Unit (ICU) and admitted to our Respiratory Intermediate Intensive Unit (RIIU), were retrospectively evaluated for outcome and weaning success. The patients, 69 +/- 9 years old, presented the following diseases: COLD (70%), cardiovascular (15%) and neuromuscular (15%). A relapse of underlying disease (62%), pneumonia (20%), thoraco-muscular pump failure (15%) and pulmonary embolism (3%) were the relapsing causes needing the ICU admission. ⋯ Maximal inspiratory pressure (31 +/- 7 cmH2O) and respiratory rate/tidal volume (83 +/- 34) were measured within 48 hours after RIIU admission. 82 subjects (75%) were weaned after 6 +/- 4 days of MV using in 87% of patients pressure support technique with spontaneous breathing cycles with oxygen supplementation. 8 patients on 109 (7%) died; 20 patients on 109 (18%) were discharged after 40 +/- 9 days of stay in RIIU necessitating home MV more than 18 hours/day by means of a tracheostomy. All patients stay in RIIU for 17 +/- 7 days with a mean cost per die of 750 thousands lire. Our data suggest that a RIIU institution for prolonged weaning in chronic diseases may be a useful solution to decrease superfluous stays in ICU decreasing costs without ba worsening in quality of care.
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Minerva anestesiologica · Jan 1996
Randomized Controlled Trial Comparative Study Clinical Trial[Spinal anesthesia in cesarean section: 1% versus 0.5% hyperbaric bupivacaine].
To compare the quality of anesthesia produced by the intrathecal administration of equivalent doses of 0.5% and 1% hyperbaric bupivacaine in patients undergoing cesarian section. ⋯ No important difference was observed in the quality of the anesthesia obtained using the intrathecal administration of equivalent doses of 1% and 0.5% solutions of hyperbaric bupivacaine in patients undergoing cesarian section. In view of the possible relationship between the neurotoxicity of local anesthetics and the concentration of the solution used for spinal anesthesia, it is to be hoped that less concentrated solutions of hyperbaric bupivacaine will be introduced in Italy compared to the 1% solution currently available.
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Minerva anestesiologica · Jan 1996
Clinical TrialPharmacokinetic profile of the induction dose of propofol in chronic renal failure patients undergoing renal transplantation.
To define the pharmacokinetic profile of the induction dose of propofol in chronic renal failure patients. ⋯ From the data gathered in this study, propofol can be considered a suitable anaesthetic agent for the induction of general anaesthesia in uraemic patients. In our opinion these data could constitute a basis for future protocols of total intravenous anaesthesia with propofol in uremic patients.
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AIM. To evaluate the validity of general anesthesia using the laryngeal mask airway (LMA) in pediatrics in a series of 163 patients. MONITORING. ⋯ Measurement of every complication during and after anesthesia. CONCLUSIONS. In pediatric anesthesia LMA represents a good link between anesthetic equipment and the patient.
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Minerva anestesiologica · Dec 1995
Clinical TrialEvaluating the difficult airway. An epidemiological study.
The epidemiological characteristics of 359 difficult intubations resulted from retrospectively collected data in a series of 4.742 individual anaesthetic case records of consecutive adult patients (2392 men, 2350 women) undergoing general anaesthesia for routine surgery. The preoperative assessment of each patient's airway was performed using standardized guidelines. Mandibular length, body weight and mobility of jaw, head and neck were evaluated with simple measurements. ⋯ Large endemic goitre and thalassaemia constitute RFs contributing occasionally to difficult airway. The positive predictive value was 61.5% and 40.9% respectively. The combination of risk-factors had a cumulative impact contributing to the high level of difficulty.