Minerva anestesiologica
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We describe our most recent findings about the use of epinephrine for cardiac arrest particularly referring to the mechanism of action, doses, modalities of administration and action on the cerebral circulation. Epinephrine is the elective drug in cardiocerebral resuscitation; but its use does not modify the final results which are still unsatisfying. The percentage of patients surviving cardiac arrest is very low, and many of them suffer important neurological damage.
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Minerva anestesiologica · Jul 1991
Randomized Controlled Trial Clinical Trial[Clonidine and postoperative shivering].
Clonidine was clinically evaluated to suppress postoperative shivering in 60 patients who had undergone anesthesia for general, thoracic and vascular surgery. The study was carried out in double blind conditions with comparison of two doses (75 and 150 micrograms) of clonidine, one dose of methylphenidate, and one dose of saline, as control group. The level of inhibition (Goldfarb scale), haemodynamics and temperature were studied. In conclusion, the methylphenidate is drug first choice for postoperative shivering, but clonidine inhibits postoperative shivering without haemodynamic and temperature variations (75 micrograms).
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Minerva anestesiologica · Jul 1991
Randomized Controlled Trial Comparative Study Clinical Trial[Drip ketamine versus ketoprofen in repeated infusions in post-cesarean section analgesia].
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Minerva anestesiologica · Jun 1991
[Survival of 213 patients who recovered in resuscitation from cardiac arrest].
213 patients who received in-hospital cardiopulmonary resuscitation (CPR) were studied over a period of five years (1985-89) to determine hospital and long-term survival. The following factors were evaluated in determining outcome: age, ECG on admission, clinical history, year, month, hour of admission. A 5-year survival table was complied for all discharged from hospital. ⋯ Hospital survival was 14.6% with an ascendant range from 1986 to 1989 (p less than 0.05); all the patients were discharged mentally unimpaired with over 50% surviving 1.5 years after discharge and 33% 5 years after. The study shows that the highest cause of cardiac arrest is ischaemic cardiopathy in male patients with an average age of 60 years. Total neurological recovery after CPR was confirmed to be a determinant predictor factor of survival.