The Journal of clinical endocrinology and metabolism
The most recent articles from:
December 2012
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J. Clin. Endocrinol. Metab. · Dec 2012
Case Reports"Hyper-warburgism," a cause of asymptomatic hypoglycemia with lactic acidosis in a patient with non-Hodgkin's lymphoma.
In cancer cells, the Warburg effect is defined as the avid consumption of glucose through the glycolytic pathway with concomitant lactate production, even under aerobic conditions. ⋯ This case represents an exaggerated Warburg effect, or "hyper-warburgism," characterized by excessive lactate production and overwhelming glucose consumption. We speculate that the decreased brain FDG uptake, despite the lack of neuroglycopenic symptoms, supports the hypothesis that lactate served as a fuel for the brain, thus protecting against hypoglycemia.
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J. Clin. Endocrinol. Metab. · Dec 2012
Case Reports Historical ArticlePituitary disease from the past: a rare case of gigantism in skeletal remains from the Roman Imperial Age.