The American journal of clinical nutrition
-
Previous trials suggest that oral l-arginine administration affects endothelial function. However, most of these studies were small, the conclusions were inconsistent, and the precise effects are therefore debatable. ⋯ Short-term oral l-arginine is effective at improving the fasting vascular endothelial function when the baseline FMD is low.
-
Review Meta Analysis
Glycemic response and health--a systematic review and meta-analysis: the database, study characteristics, and macronutrient intakes.
Reduction of dietary glycemic response has been proposed as a means of reducing the risk of diabetes and coronary heart disease. Its role in health maintenance and management, alongside unavailable carbohydrate (eg, fiber), is incompletely understood. ⋯ Among GI studies, observed reductions in glycemic load are most often not solely due to substitution of high for low glycemic carbohydrate foods. Available carbohydrate intake is a confounding factor. The role of unavailable carbohydrate remains to be accounted for.
-
Review Meta Analysis
Glycemic response and health--a systematic review and meta-analysis: relations between dietary glycemic properties and health outcomes.
Reduction of dietary glycemic response has been proposed as a means of reducing the risk of diabetes and coronary heart disease. The impact of glycemic response on markers of health remains to be elucidated. ⋯ Consumption of reduced glycemic response diets are followed by favorable changes in the health markers examined. The case for the use of such diets looks compelling. Unavailable carbohydrate intake is equally important.
-
Meta Analysis
Vitamin-mineral supplementation and the progression of atherosclerosis: a meta-analysis of randomized controlled trials.
Laboratory and observational studies suggest that antioxidant and B vitamin supplementation may prevent atherosclerosis. Although trials have not shown a benefit of these supplements on clinical cardiovascular events, it is unknown whether they affect the progression of atherosclerosis as measured by imaging techniques. ⋯ Our meta-analysis showed no evidence of a protective effect of antioxidant or B vitamin supplements on the progression of atherosclerosis, thus providing a mechanistic explanation for their lack of effect on clinical cardiovascular events.
-
Meta Analysis
Association between fruit and vegetable consumption and oral cancer: a meta-analysis of observational studies.
Oral cancer ranks as the seventh most common form of cancer worldwide. Recent reports have examined the effect of fruit and vegetable intake on the risk of oral cancer, but results are controversial. ⋯ The consumption of fruit and vegetables is associated with a reduced risk of oral cancer.