The Journal of thoracic and cardiovascular surgery

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• J. Thorac. Cardiovasc. Surg. · Apr 2021

  Pulsed ultrasound attenuates the hyperglycemic exacerbation of myocardial ischemia-reperfusion injury.

  Acute hyperglycemia during myocardial infarction worsens outcomes in part by inflammatory mechanisms. Pulsed ultrasound has anti-inflammatory potential in bone healing and neuromodulation. We hypothesized that pulsed ultrasound would attenuate the hyperglycemic exacerbation of myocardial ischemia-reperfusion injury via the cholinergic anti-inflammatory pathway. ⋯ Pulsed ultrasound treatment of the spleen or neck attenuated the hyperglycemic exacerbation of myocardial ischemia-reperfusion injury leading to a 3-fold decrease in infarct size. Pulsed ultrasound may provide cardioprotection via the cholinergic anti-inflammatory pathway and could be a promising new nonpharmacologic, noninvasive therapy to reduce infarct size during acute myocardial infarction and improve patient outcomes.

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• J. Thorac. Cardiovasc. Surg. · Apr 2021

  Editorial Comment

  Commentary: Toward achieving precision in the management of postcardiotomy failure.

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• J. Thorac. Cardiovasc. Surg. · Apr 2021

  Editorial Comment Letter

  Commentary: Additional "customized" aortopulmonary shunt may increase "vis a tergo" to rescue a failing bidirectional cavopulmonary shunt.

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• J. Thorac. Cardiovasc. Surg. · Apr 2021

  Editorial Comment

  Commentary: Annular reduction of the tricuspid valve-maybe less, maybe a little more?

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• J. Thorac. Cardiovasc. Surg. · Apr 2021

  Editorial Comment

  Commentary: Rejuvenation of a trusted tool.

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