The Journal of thoracic and cardiovascular surgery
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J. Thorac. Cardiovasc. Surg. · May 2021
Editorial CommentCommentary: "Get moving early!" Inpatient cardiac rehabilitation reduces unplanned hospitalizations.
Inpatient multidisciplinary cardiac rehabilitation is associated with lower unplanned hospital readmissions, compared to conventional cardiac rehabilitation, among patients undergoing cardiac surgery.
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J. Thorac. Cardiovasc. Surg. · May 2021
Nucleophosmin contributes to vascular inflammation and endothelial dysfunction in atherosclerosis progression.
It is unclear whether nucleophosmin (NPM) participates in cardiovascular disease. The present study aimed to investigate the role and underlying mechanisms of NPM in atherosclerosis. ⋯ These data provide novel evidence that NPM promotes atherosclerosis by inducing vascular inflammation and endothelial dysfunction through the NF-κB signaling pathway and suggest that NPM may be a promising target for atherosclerosis prevention and treatment.
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J. Thorac. Cardiovasc. Surg. · May 2021
Body mass index and early outcomes following mitral valve surgery for degenerative disease.
Using a large national database, we sought to better define the relationship between obesity measures and early clinical outcomes following mitral valve surgery for degenerative disease. ⋯ Although individual measures of obesity were not associated with an increased mortality risk on regression modeling, the U-shaped relationship between mortality and increasing BMI demonstrates lower mortality risks in lower obesity classes. Increasing BMI was associated with an increased hazard for DSWI.
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J. Thorac. Cardiovasc. Surg. · May 2021
Effects of acute-phase multidisciplinary rehabilitation on unplanned readmissions after cardiac surgery.
The provision of inpatient programs that reduce the incidence of readmission after cardiac surgery remains challenging. Investigators have focused on multidisciplinary cardiac rehabilitation (CR) because it reduces the postoperative readmission rate; however, most previous studies used outpatient models (phase II CR). We retrospectively investigated the effect of comprehensive multidisciplinary interventions in the acute inpatient phase (phase I CR) on unplanned hospital readmission. ⋯ In phase I, compared to conv-CR alone, multi-CR reduced the incidence of unplanned readmission. Early multidisciplinary CR can reduce hospitalizations and improve long-term prognosis after cardiac surgery.
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J. Thorac. Cardiovasc. Surg. · May 2021
Deceased-donor lobar lung transplant: A successful strategy for small-sized recipients.
Lobar lung transplantation (LLTx) from deceased donors is a potential solution for donor-recipient size mismatch for small sized recipients. We reviewed our institutional experience to compare outcomes after LLTx to standard lung transplantation (LTx). ⋯ Although LLTx is a high-risk procedure, both mid- and long-term survival are comparable with LTx in all cohorts in the modern era. LLTx therefore represents a valuable surgical option for small-sized recipients.