The Journal of thoracic and cardiovascular surgery
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J. Thorac. Cardiovasc. Surg. · Jun 2022
Multicenter Study Clinical TrialNeoadjuvant pemetrexed plus cisplatin followed by pleurectomy for malignant pleural mesothelioma.
Despite becoming the preferred surgical technique for malignant pleural mesothelioma, pleurectomy/decortication has received few prospective clinical trials. Therefore, the Japan Mesothelioma Interest Group conducted a prospective multi-institutional study to evaluate the feasibility of neoadjuvant chemotherapy followed by pleurectomy/decortication. ⋯ Neoadjuvant chemotherapy followed by pleurectomy/decortication was feasible with acceptable survival and mortality/morbidity. Postoperative pulmonary function was approximately 80% of the preoperative pulmonary function.
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J. Thorac. Cardiovasc. Surg. · Jun 2022
Surgical management strategy of slide tracheoplasty for infants with congenital tracheal stenosis.
The study objective was to evaluate the outcomes of slide tracheoplasty in infancy and identify predictors of adverse outcomes. ⋯ A tailored individual management strategy of slide tracheoplasty in infancy facilitates favorable clinical outcomes. Close postoperative follow-up and long-term functional evaluations including clinical symptoms and pulmonary function are still needed.
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J. Thorac. Cardiovasc. Surg. · Jun 2022
Multicenter StudyCharacteristics and outcomes of patients with COVID-19 supported by extracorporeal membrane oxygenation: A retrospective multicenter study.
To determine characteristics, outcomes, and clinical factors associated with death in patients with COVID-19 requiring extracorporeal membrane oxygenation (ECMO) support. ⋯ In patients with severe COVID-19 necessitating ECMO support, in-hospital mortality occurred in fewer than half of the cases. ECMO might serve as a viable modality for terminally ill patients with refractory COVID-19.
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J. Thorac. Cardiovasc. Surg. · Jun 2022
Influence of surgical volume on outcomes in low-risk patients undergoing isolated surgical aortic valve replacement.
Intermediate- and high-risk patients undergoing isolated surgical aortic valve replacement have superior outcomes at higher-volume compared with lower-volume hospitals. This study examines the impact of hospital volume on outcomes in low-risk patients undergoing aortic valve replacement. ⋯ Operative mortality in low-risk patients undergoing aortic valve replacement is higher in low-volume compared with high-volume hospitals. The probability of a major complication, such as renal failure, is also greater in low-volume hospitals. The relationship between volume and outcomes in low-risk patients will require more research to understand the causes and design appropriate interventions.
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J. Thorac. Cardiovasc. Surg. · Jun 2022
Adverse events after coronary artery bypass grafting in patients with preoperative metabolic syndrome: A 10-year follow-up of the Veterans Affairs Database.
Data regarding 10-year survival and adverse cardiovascular events in patients with metabolic syndrome (MET) after coronary artery bypass grafting (CABG) is limited. ⋯ Patients with metabolic syndrome undergoing coronary artery bypass grafting have higher 10-year cardiovascular event rates.