The Journal of thoracic and cardiovascular surgery
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J. Thorac. Cardiovasc. Surg. · Dec 2023
Aortic valve reimplantation in patients with connective tissue disorders: Are the leaflets durable?
The durability of reimplanted myxomatous aortic valves in root replacements for patients with connective tissue disorders (CTD) is unclear; therefore, we sought to evaluate the long-term resilience of these repairs. ⋯ Aortic valve reimplantation is a durable operation in patients with CTD and root aneurysms. These patients do not experience early degeneration of their reimplanted aortic valves.
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J. Thorac. Cardiovasc. Surg. · Dec 2023
Is the practice of using oversized organs for recipients with elevated pulmonary vascular resistance justified?
The purpose of this study was to assess post-transplantation outcomes in recipients with increased pulmonary vascular resistance (PVR) in relation to donor size. ⋯ Despite a persistent practice pattern to transplant oversized organs in high-PVR patients, there remains no difference in post-transplantation survival among these patients and those who received smaller organ transplants. Therefore, transplants in patients with high PVR should not be delayed by waiting for larger donors.
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J. Thorac. Cardiovasc. Surg. · Dec 2023
Quantifying the effects of circulatory arrest on acute kidney injury in aortic surgery.
We aim to investigate the association between parameters surrounding circulatory arrest and postoperative acute kidney injury in aortic surgery. ⋯ Within the range of our clinical practice, prolonged lower-body ischemia duration was not independently associated with postoperative acute kidney injury, whereas nadir temperature was.
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J. Thorac. Cardiovasc. Surg. · Dec 2023
Stem Cell-Derived Exosome Patch with Coronary Artery Bypass Graft Restores Cardiac Function in Chronically Ischemic Porcine Myocardium.
This study aimed to investigate whether or not the application of a stem cell-derived exosome-laden collagen patch (EXP) during coronary artery bypass grafting (CABG) can recover cardiac function by modulating mitochondrial bioenergetics and myocardial inflammation in hibernating myocardium (HIB), which is defined as myocardium with reduced blood flow and function that retains viability and variable contractile reserve. ⋯ Exosomes recovered cardiomyocyte mitochondrial respiration and reduced myocardial inflammation through paracrine signaling, resulting in improved cardiac function.
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J. Thorac. Cardiovasc. Surg. · Dec 2023
A uniform strategy of primary repair of tetralogy of Fallot - Transventricular approach results in low reoperation rate in the first decade.
To review outcomes after a uniform strategy of transventricular repair of tetralogy of Fallot. ⋯ A uniform strategy of primary repair of tetralogy of Fallot through a transventricular approach resulted in low reoperation rate in the first decade. The need of pulmonary valve implantation was limited to <4% at 10 years.