The Journal of thoracic and cardiovascular surgery
-
J. Thorac. Cardiovasc. Surg. · Dec 2024
Rise of the Machines - Normothermic Regional Perfusion Use in Heart Transplantation in the United States.
Normothermic regional perfusion (NRP) and direct procurement and perfusion (DPP) allow for transplantation with donation after circulatory death (DCD) hearts. This study aimed to characterize the use of and variations in NRP and DPP for DCD transplants in the United States. ⋯ The use of NRP is increasing in the United States, with tremendous growth seen since its introduction several years ago. Significant variation remains in the use of NRP and DPP, and further exploration of the impact of each procurement and preservation strategy on transplantation outcomes is needed.
-
J. Thorac. Cardiovasc. Surg. · Dec 2024
Lung Transplant Outcomes in Recipients of Advanced Age: Are Two Always Better Than One?
Lung transplantation has become more common in patients aged 65 years and older. We aimed to examine outcomes across age groups and identify risk factors for decreased survival. ⋯ Bilateral lung transplantation offers a survival advantage over single lung transplantation in recipients up to 74 years of age. Recipients aged 75 to 79 have poor long-term survival. Previous cardiac surgery is associated with worse long-term survival, necessitating careful patient selection, especially in older patients being offered a single lung transplant.