The Journal of thoracic and cardiovascular surgery
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J. Thorac. Cardiovasc. Surg. · Sep 2002
Comparative StudySurgical options and results of repeated aortic root replacement for failed aortic allografts placed in childhood.
This report reviews our experience with repeated aortic root replacement after failure of cryopreserved aortic allografts placed during childhood and compares replacement with aortic allografts, pulmonary autografts, and mechanical valved conduits in these patients. ⋯ Replacement of cryopreserved aortic root allografts placed during childhood is safe. Five-year pulmonary autograft durability is excellent, although the risk of early failure may be increased. Differences in 5-year conduit longevity were not detectable.
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J. Thorac. Cardiovasc. Surg. · Sep 2002
Comparative StudyA respiratory gas exchange catheter: in vitro and in vivo tests in large animals.
Acute respiratory failure is associated with a mortality of 40% to 50%, despite advanced ventilator support and extracorporeal membrane oxygenation. A respiratory gas exchange catheter (the Hattler Catheter) has been developed as an oxygenator and carbon dioxide removal device for placement in the vena cava and right atrium in the treatment of acute respiratory failure to improve survival. ⋯ Progress has been made toward developing an intravenous gas exchange catheter to provide temporary pulmonary support for patients in acute respiratory failure.
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J. Thorac. Cardiovasc. Surg. · Aug 2002
Aggressive management of lung donors classified as unacceptable: excellent recipient survival one year after transplantation.
A dire shortage of lungs for transplantation exists. We hypothesized that aggressive organ procurement organization management of lungs usually rated as unacceptable (ratio of Pao(2) to inspired oxygen fraction <150) might make them acceptable for transplantation. We also hypothesized that lungs from donors who died of trauma could be used for transplantation with recipient survival comparable with that seen with lungs from donors who died of nontraumatic causes. ⋯ Aggressive organ procurement organization management of donors initially considered unacceptable may increase the number of lungs available for transplantation.