J Am Board Fam Med
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Counsel patients that their Mirena IUD retains contraceptive effectiveness for extended use up to 8 years.1 The cumulative failure rate for years 6 through 8 was 0.68%, similar to reported rates for the first 5 years of use.
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Consider prescribing doxycycline as prophylaxis for bacterial sexually transmitted infections (STIs) in certain clinical scenarios. New data suggests that a one-time dose of 200 mg doxycycline taken within 72 hours of an unprotected sexual encounter may reduce transmission of syphilis, gonorrhea and chlamydia by a combined two thirds in a high-risk population.
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Use the new eGFRcr-cys equation (estimated glomerular filtration rate equation that incorporates both serum creatinine and serum cystatin C levels) to estimate the GFR for both Black and non-Black individuals because the equation has improved accuracy, minimizes differences in eGFR between race groups, and more accurately reflects chronic kidney disease (CKD) prognosis while eliminating the use of race in GFR estimating equations.