Plos One
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Involving the autism community in research increases the real-world translation and impact of findings. The current study explored the research priorities of parents of school-aged children on the autism spectrum across the home, school, and community settings. ⋯ The Q-sort method highlighted different top priorities, with understanding the parent, sibling, child and family impact and stress the highest ranked priority for home, teacher/staff education and support for the school, and recognizing and supporting anxiety for the community. The implications of the findings are discussed in relation to shifting the framework of autism research to align research agendas with parental priorities.
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The response to the COVID-19 epidemic is generating severe shortages of personal protective equipment around the world. In particular, the supply of N95 respirator masks has become severely depleted, with supplies having to be rationed and health care workers having to use masks for prolonged periods in many countries. We sought to test the ability of 7 different decontamination methods: autoclave treatment, ethylene oxide gassing (ETO), low temperature hydrogen peroxide gas plasma (LT-HPGP) treatment, vaporous hydrogen peroxide (VHP) exposure, peracetic acid dry fogging (PAF), ultraviolet C irradiation (UVCI) and moist heat (MH) treatment to decontaminate a variety of different N95 masks following experimental contamination with SARS-CoV-2 or vesicular stomatitis virus as a surrogate. ⋯ Pleated, layered non-woven fabric N95 masks retained integrity in fit testing for at least 10 cycles of autoclaving but the molded N95 masks failed after 1 cycle; filtration testing however was intact to 5 cycles for all masks. The successful application of autoclaving for layered, pleated masks may be of particular use to institutions globally due to the virtually universal accessibility of autoclaves in health care settings. Given the ability to modify widely available heating cabinets on hospital wards in well-resourced settings, the application of moist heat may allow local processing of N95 masks.
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When patients with acute respiratory distress syndrome are moved out of an intensive care unit, the ventilator often requires changing. This procedure suppresses positive end expiratory pressure and promotes lung derecruitment. Clamping the endotracheal tube may prevent this from occurring. Whether or not such clamping maintains positive end-expiratory pressure has never been investigated. We designed a bench study to explore this further. ⋯ Only the Extra Corporeal Membrane Oxygenation clamp was efficient. Even with an Extra Corporeal Membrane Oxygenation clamp, it is important to limit the duration the ventilator is disconnected to a few seconds (ideally 5 s).
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The use of biomass fuel is associated with the deterioration of human health and women are more likely to develop health conditions due to their exposure to indoor air pollution during cooking. This study was conducted to assess the pattern of fuel used for cooking in households as well as to determine the association between the types of fuel used with respect to socio-demographic characteristics and health status of women. A community based cross-sectional survey was conducted between August 2016 and September 2018 in four rural areas and one semi-urban area of Udupi district, Karnataka, India. ⋯ A positive trend was observed between cumulative exposure to biomass in hour-years and various self-reported health symptoms/conditions (p < 0.001). It was observed that more than two-thirds of women using biomass fuel for cooking were positively associated with self-reported health symptoms. Further longitudinal studies are essential to determine the level of harmful air pollutants in household environment and its association with various health conditions among women in this region.
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Information and Communication Technology (ICT) has been a key agent of change in the 21st century. Given the role of ICT in changing society, this research explores the responses and attitudes to change over time from ICT professionals and ICT academics in dealing with the potentially far reaching political challenge triggered by the UK's 2016 European Union Referendum and its decision to leave the European Union (Brexit). Whilst the vote was a UK based decision its ramifications have global implications and as such the research was not confined to the UK. This article presents the second phase of the research at the mid-point in the UK/European Union (EU) Brexit process, thus complementing the findings gathered immediately after the Referendum decision. The fundamental question being researched was: What are ICT professionals' personal and professional perspectives on the change triggered by Brexit in terms of opportunities and threats? ⋯ Data was collected through a survey launched in March 2018, one year on from the UK's triggering of Article 50 and marking the mid-point in the two-year Brexit process. The survey replicated the one delivered at the point of the Referendum decision in 2016 with some developments. In addition, two appreciative inquiry focus groups were conducted. The research sought to understand any shifting perspectives on the opportunities and threats that would exist post-Brexit for ICT professionals and academics. 59% of survey participants were negative regarding the Brexit decision. Participants noted the position post-Brexit for the UK, and the remaining 27 EU Member States (EU27), was still very uncertain at this stage. They observed that planned change versus uncertainty provides for very different responses. In spite of the uncertainty, the participants were able to consider and advocate for potential opportunities although these were framed from national perspectives. The opportunities identified within the appreciative inquiry focus groups aligned to those recorded by survey participants with similar themes highlighted. However, the optimum conditions for change have yet to be reached as there is still not an informed position, message and clear leadership with detailed information for the ICT context. Further data will be gathered after the UK exit from the EU, assuming this occurs.