Pediatrics
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Randomized Controlled Trial Comparative Study
Oral sucrose and "facilitated tucking" for repeated pain relief in preterms: a randomized controlled trial.
To test the comparative effectiveness of 2 nonpharmacologic pain-relieving interventions administered alone or in combination across time for repeated heel sticks in preterm infants. ⋯ Sucrose with and without FT had pain-relieving effects even in preterm infants of <32 weeks of gestation having repeated pain exposures. These interventions remained effective during repeated heel sticks across time. FT was not as effective and cannot be recommended as a nonpharmacologic pain relief intervention for repeated pain exposure.
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Randomized Controlled Trial
Peer-led education for adolescents with asthma in Jordan: a cluster-randomized controlled trial.
To determine the impact of a peer-led education program, developed in Australia, on health-related outcomes in high school students with asthma in Jordan. ⋯ This trial demonstrated that the Adolescent Asthma Action program can be readily adapted to suit different cultures and contexts. Adolescents in Jordan were successful in teaching their peers about asthma self-management and motivating them to avoid smoking. The findings revealed that peer education can be a useful strategy for health promotion programs in Jordanian schools when students are given the opportunity and training.
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Randomized Controlled Trial Multicenter Study Comparative Study
Disability 3, 12, and 24 months after traumatic brain injury among children and adolescents.
To examine disability in children and adolescents after traumatic brain injury (TBI) across the spectrum of injury severity. ⋯ Children with moderate or severe TBI and children with mild TBI who had intracranial hemorrhage had substantial long-term reduction in their quality of life, participation in activities with others, and ability to communicate and care for themselves.
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Randomized Controlled Trial Multicenter Study Comparative Study
Randomized trial comparing 3 approaches to the initial respiratory management of preterm neonates.
We designed a multicenter randomized trial to compare 3 approaches to the initial respiratory management of preterm neonates: prophylactic surfactant followed by a period of mechanical ventilation (prophylactic surfactant [PS]); prophylactic surfactant with rapid extubation to bubble nasal continuous positive airway pressure (intubate-surfactant-extubate [ISX]) or initial management with bubble continuous positive airway pressure and selective surfactant treatment (nCPAP). ⋯ Preterm neonates were initially managed with either nCPAP or PS with rapid extubation to nCPAP had similar clinical outcomes to those treated with PS followed by a period of mechanical ventilation. An approach that uses early nCPAP leads to a reduction in the number of infants who are intubated and given surfactant.
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Randomized Controlled Trial Comparative Study
Hypotonic versus isotonic maintenance fluids after surgery for children: a randomized controlled trial.
The objective of this randomized controlled trial was to evaluate the risk of hyponatremia following administration of a isotonic (0.9% saline) compared to a hypotonic (0.45% saline) parenteral maintenance solution (PMS) for 48 hours to postoperative pediatric patients. ⋯ Isotonic PMS is significantly safer than hypotonic PMS in protecting against acute postoperative hyponatremia in children.