Obes Res Clin Pract
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Obes Res Clin Pract · Jul 2013
Multicenter Study Comparative StudyComparative effectiveness of bariatric surgery vs. nonsurgical treatment of type 2 diabetes among severely obese adults.
Although all weight-loss approaches may improve insulin sensitivity in type 2 diabetes, bariatric surgery is believed to be the only reliable means of achieving diabetes remission. We conducted a retrospective cohort study to compare rates of diabetes remission, relapse and all-cause mortality among severely obese individuals with diabetes who underwent bariatric surgery vs. nonsurgically treated individuals. Severely obese adults with uncontrolled or medication-controlled diabetes who underwent bariatric surgery or received usual medical care from 2005 to 2008 in three health care delivery systems in the United States were eligible. ⋯ Age, site, duration of diabetes, hemoglobin A1c level, and intensity of diabetes medication treatment were significantly associated with remission. Bariatric subjects also experienced lower relapse rates than nonsurgical subjects (adjusted HR: 0.19; 95% CI: 0.15-0.23) with no higher risk of death (adjusted HR: 0.54; 95% CI: 0.22-1.30). We conclude that bariatric surgery can effectively induce remission of diabetes among most severely obese adults, and this treatment approach appears to be superior to nonsurgical treatment in inducing diabetes remission.
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Fructose is a monosaccharide and reducing sugar. It is present in sucrose and honey. ⋯ In this review, we discuss that how fructose causes fatty liver, obesity and insulin resistance. We also discuss the effects of consumption of high fructose corn syrup, dietary fructose, fructose-induced changes in metabolism.:
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Obes Res Clin Pract · Jan 2013
Association between obesity and various parameters of physical fitness in Korean students.
The purpose of this study was to evaluate the association between the types of obesity classified according to the body mass index (BMI) and/or waist circumference (WC) and the various parameters of physical fitness in Korean college students. BMI, WC, and fitness assessments were performed on 726 male college student volunteers who visited a public health center in Seoul, Korea. ⋯ The odds ratios (OR) (95% confidence interval [CI]) of the BOG and WOG for the 1.5-km run were 0.367 (0.192-0.701) and 0.168 (0.037-0.773), respectively; of the BWOG and WOG for vital capacity were 5.900 (1.298-26.827) and 5.364 (1.166-24.670), respectively; of the BOG for push-ups was 0.517 (0.279-0.959); of the WOG for back strength was 0.206 (0.045-0.945); of the BWOG and BOG for grip strength were 5.973 (1.314-27.157) and 2.036 (1.089-3.807), respectively; and of the BOG for the whole body reaction time was 0.405 (0.212-0.774), as compared to the NG. We conclude that all 3 types of obesity (classified into the BWOG, BOG, and WOG) result in reduced cardiorespiratory and muscular endurance, but increased muscular strength and vital capacity.
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Obes Res Clin Pract · Oct 2011
Decreased plasma B-type natriuretic peptide levels in obesity are not explained by altered left ventricular hemodynamics.
⋯ We found that increased BMI was associated with LV diastolic abnormalities without change in systolic function and that patients with increased BMI had reduced plasma BNP levels despite having elevated EDP. These results suggest that the reduced BNP levels in obesity are not explained by altered LV hemodynamics.
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Obes Res Clin Pract · Nov 2009
Proinflammatory and phagocytic functions of alveolar macrophages in obesity.
⋯ Our data suggest that in the absence of underlying comorbidities, the increased frequency of respiratory infections in obesity cannot be explained by impairment of alveolar macrophages. Further work is required to delineate the relationship between obesity and the noncellular aspects of innate immunity.