Pediatr Crit Care Me
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Pediatr Crit Care Me · Jul 2011
Flexible bronchoscopy for children on extracorporeal membrane oxygenation for cardiac failure.
To describe the safety and use of flexible bronchoscopy in the management of respiratory complications in patients on extracorporeal membrane oxygenation for cardiac failure. ⋯ In patients requiring extracorporeal membrane oxygenation for cardiac failure, flexible bronchoscopy can be performed safely, provide important diagnostic information to the bedside clinician, and, perhaps, therapeutic benefit to the patient.
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Pediatr Crit Care Me · Jul 2011
Association of bacterial pneumonia and respiratory failure in children with community-acquired influenza infection.
To investigate the association of bacterial pneumonia and respiratory failure in children with community-acquired influenza infection presenting to a pediatric intensive care unit. ⋯ Our findings suggest that bacterial pneumonia was associated with increased odds of respiratory failure in both previously healthy children and those with chronic medical conditions. Early aggressive therapy should be considered for patients with severe influenza.
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Pediatr Crit Care Me · Jul 2011
Comparative Study Clinical TrialEvaluation of a new pediatric continuous oximetry catheter.
To evaluate the accuracy of central venous oxygen saturation recordings from a new in-line pediatric oximetry catheter. ⋯ In this limited number of patients, use of the PediaSat venous oximetry catheter was safe and had good agreement with co-oximetry-measured values.
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Pediatr Crit Care Me · Jul 2011
Brain-systemic temperature gradient is temperature-dependent in children with severe traumatic brain injury.
To understand the gradient between rectal and brain temperature in children after severe traumatic brain injury. We hypothesized that the rectal temperature and brain temperature gradient will be influenced by the child's body surface area and that this relationship will persist over physiologic temperature ranges. ⋯ Brain temperature and rectal temperature are generally well-correlated in children with traumatic brain injury. This relationship is different at the extremes of the physiologic temperature range, with the temperature gradient reversed during brain hypothermia and hyperthermia. Given that studies showing neuroprotection from hypothermia in animal models of brain injury generally target brain temperature, our data suggest the possibility that, if brain temperature were the therapeutic target in clinical trials, this would result in somewhat higher systemic temperature and potentially fewer side effects. This relationship may be exploited in future clinical trials to maintain brain hypothermia (for neurologic protection) at slightly higher systemic temperatures (and potentially fewer systemic side effects).