Pediatr Crit Care Me
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Pediatr Crit Care Me · Jan 2012
Invasive intracranial pressure monitoring is a useful adjunct in the management of severe hepatic encephalopathy associated with pediatric acute liver failure.
Pediatric acute liver failure is often accompanied by hepatic encephalopathy, cerebral edema, and raised intracranial pressure. Elevated intracranial pressure can be managed more effectively with intracranial monitoring, but acute-liver-failure-associated coagulopathy is often considered a contraindication for invasive monitoring due to risk for intracranial bleeding. We reviewed our experience with use of early intracranial pressure monitoring in acute liver failure in children listed for liver transplantation. ⋯ In our series of patients, intracranial pressure monitoring had a low complication rate and was associated with a high survival rate despite severe hepatic encephalopathy and cerebral edema in the setting of pediatric acute liver failure. In our experience, monitoring of intracranial pressure allowed interventions to treat increased intracranial pressure and provided additional information regarding central nervous system injury before liver transplant. Further study is warranted to confirm if monitoring allows more directed intracranial pressure therapy and improves survival in pediatric acute liver failure.
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Previous simulation studies suggest that temporary pediatric mass critical care approaches would accommodate plausible hypothetical sudden-impact public health emergencies. However, the utility of sustained pediatric mass critical care responses in prolonged pandemics has not been evaluated. The objective of this study was to compare the ability of a typical region to serve pediatric intensive care unit needs in hypothetical pandemics, with and without mass critical care responses sufficient to triple usual pediatric intensive care unit capacity. DESIGN, SETTING, PATIENTS, AND INTERVENTIONS: The Monte Carlo simulation method was used to model responses to hypothetical pandemics on the basis of national historical evidence regarding pediatric intensive care unit admission and length of stay in pandemic and nonpandemic circumstances. Assuming all ages are affected equally, federal guidelines call for plans to serve moderate and severe pandemics requiring pediatric intensive care unit care for 457 and 5,277 infants and children per million of the population, respectively. ⋯ Mass critical care approaches would be essential to extend care to the majority of infants and children in a severe pandemic. However, some patients needing critical care still could not be accommodated, requiring consideration of rationing.
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Pediatr Crit Care Me · Jan 2012
Comparative StudyExtracorporeal membrane oxygenation support for intractable primary arrhythmias and complete congenital heart block in newborns and infants: short-term and medium-term outcomes.
To describe the experience with extracorporeal membrane oxygenation support for intractable primary arrhythmias in newborns and infants. ⋯ The requirement of extracorporeal membrane oxygenation support in newborns and infants with intractable arrhythmia is rare. Extracorporeal membrane oxygenation support does potentially carry morbidity; however, to prevent arrhythmia-related mortality, extracorporeal membrane oxygenation support and/or extracorporeal cardiopulmonary resuscitation should be considered in the management of hemodynamically unstable primary arrhythmias as an emergent lifesaving procedure.
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Pediatr Crit Care Me · Jan 2012
Comparative StudyThe association between the end tidal alveolar dead space fraction and mortality in pediatric acute hypoxemic respiratory failure.
To investigate the relationship of markers of oxygenation, PaO2/FIO2 ratio, SpO2/FIO2 ratio, oxygenation index, oxygen saturation index, and dead space (end tidal alveolar dead space fraction) with mortality in children with acute hypoxemic respiratory failure. ⋯ In pediatric acute hypoxemic respiratory failure, easily obtainable pulmonary specific markers of disease severity (SpO2/FIO2 ratio, oxygen saturation index, and the end tidal alveolar dead space fraction) may be useful for the early identification of children at high risk of death. Furthermore, the end tidal alveolar dead space fraction should be considered for risk stratification of children with acute hypoxemic respiratory failure, given that it was independently associated with mortality.
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Pediatr Crit Care Me · Jan 2012
Comparative StudyIdentifying factors to minimize phlebotomy-induced blood loss in the pediatric intensive care unit.
Phlebotomy-induced blood loss in critically ill children is common, contributes to anemia, and may be avoidable. We aimed to identify factors associated with phlebotomy-induced blood loss. ⋯ Blood drawn in excess of phlebotomy requirements exceeds the blood volume loss drawn for phlebotomy by two fold. Using indwelling catheters for phlebotomy often requires a discard volume to be drawn before obtaining the laboratory sample. Consolidating phlebotomy tests and using a closed system may decrease the amount of blood overdrawn and minimize overall phlebotomy-induced blood loss.