Pediatr Crit Care Me
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Pediatr Crit Care Me · Feb 2015
Effect of High-Dose Continuous Albuterol Nebulization on Clinical Variables in Children With Status Asthmaticus.
Continuous albuterol nebulization is generally administered at 2.5-20 mg/hr at most centers. We examined the effect of high-dose (75 or 150 mg/hr) albuterol on clinical variables in children with status asthmaticus. ⋯ High-dose continuous albuterol nebulization is associated with a low rate of subsequent mechanical ventilation and fairly short PICU length of stay without significant toxicity. Prospective studies comparing conventional and high-dose albuterol nebulization are needed to determine the optimum dose providing maximum efficacy with the least adverse effects.